ENSDARG00000069937


Danio rerio

Features
Gene ID: ENSDARG00000069937
  
Biological name :dnm2a
  
Synonyms : dnm2a / dynamin 2a
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 47130912
Gene end: 47213115
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000135475
Ensembl peptide - ENSDARP00000025652
Ensembl peptide - ENSDARP00000134807
NCBI entrez gene - 559334     See in Manteia.
RefSeq - NM_001030128
RefSeq - XM_005164243
RefSeq Peptide - NP_001025299
swissprot - Q4V8Z7
swissprot - T1SXK0
swissprot - A0A0R4IIR1
ZFIN ID - ZDB-GENE-050913-84
Ensembl - ENSDARG00000069937
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dnm1a / dynamin 1a / DNM1* / P39053* / Q05193* / dynamin 1*ENSDARG0000001004277
dnm1b / dynamin 1b / DNM1* / P39053* / Q05193* / dynamin 1*ENSDARG0000000928177
dnm3a / dynamin 3aENSDARG0000003223871
dnm2b / dynamin 2b / DNM2* / P50570* / dynamin 2*ENSDARG0000010305445
dnm1l / Q7SXN5 / dynamin 1-like / O00429* / Q8K1M6* / Dynamin-1-like protein *ENSDARG0000001500634
si:dkey-32e23.4ENSDARG0000006315933
CABZ01092282.1ENSDARG0000010014532
mxa / myxovirus (influenza) resistance AENSDARG0000002168823
mxb / myxovirus (influenza) resistance BENSDARG0000000495321
mxf / myxovirus (influenza virus) resistance FENSDARG0000002604920
mxg / myxovirus (influenza virus) resistance GENSDARG0000000801920
mxe / Q800G5 / myxovirus (influenza virus) resistance E / MX1* / MX2* / P20591* / P20592* / Q9WVP9* / MX dynamin like GTPase 2* / MX dynamin like GTPase 1* / Mus musculus MX dynamin-like GT...ENSDARG0000001442720
mxc / Q6DKF0 / myxovirus (influenza virus) resistance C / MX1* / MX2* / Q9WVP9* / P20591* / P20592* / MX dynamin like GTPase 2* / MX dynamin like GTPase 1* / Mus musculus MX dynamin-like GT...ENSDARG0000002478919
mxd / myxovirus (influenza virus) resistance DENSDARG0000002336919
si:dkeyp-110c12.3ENSDARG0000005179519
CABZ01084501.2 / DNM2* / P50570* / dynamin 2*ENSDARG0000011333217


Protein motifs (from Interpro)
Interpro ID Name
 IPR000375  Dynamin central domain
 IPR001401  Dynamin, GTPase domain
 IPR001849  Pleckstrin homology domain
 IPR003130  Dynamin GTPase effector
 IPR011993  PH-like domain superfamily
 IPR019762  Dynamin, GTPase region, conserved site
 IPR020850  GTPase effector domain
 IPR022812  Dynamin superfamily
 IPR027188  Dynamin-2
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030381  Dynamin-type guanine nucleotide-binding (G) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000266 mitochondrial fission IBA
 biological_processGO:0003374 dynamin family protein polymerization involved in mitochondrial fission IBA
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0043009 chordate embryonic development IMP
 biological_processGO:0060026 convergent extension IMP
 biological_processGO:0061025 membrane fusion IBA
 biological_processGO:0061053 somite development IMP
 biological_processGO:0061061 muscle structure development IMP
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0031966 mitochondrial membrane IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0008017 microtubule binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000084 yolk yolk edematous , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000114 heart heart Z disc blurry , abnormal
heart sarcolemma edematous , abnormal
heart decreased functionality , abnormal
heart apoptotic , abnormal
Show

 ZFA:0000135 notochord notochord decreased length , abnormal
notochord bent , abnormal
Show

 ZFA:0000155 somite somite condensed , abnormal
somite decreased size , abnormal
somite shortened , abnormal
somite hypoplastic , abnormal
Show

 ZFA:0000473 trunk musculature trunk musculature myofibril decreased size , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased length , abnormal
whole organism dead , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved , abnormal
post-vent region bent , abnormal
post-vent region myofibril disorganized , abnormal
Show

 ZFA:0001285 intersegmental vessel intersegmental vessel increased branchiness , abnormal
intersegmental vessel sprouting angiogenesis process quality , abnormal
Show

 ZFA:0001319 myocardium myocardium degenerate , abnormal
Show

 ZFA:0001377 presumptive mesoderm presumptive mesoderm decreased length , abnormal
Show

 ZFA:0005145 muscle muscle disorganized , abnormal
Show

 ZFA:0009115 skeletal muscle cell skeletal muscle cell morphology , abnormal
skeletal muscle cell disorganized , abnormal
skeletal muscle cell increased diameter , abnormal
skeletal muscle cell nucleus increased amount , abnormal
skeletal muscle cell skeletal muscle myofibril disorganized , abnormal
skeletal muscle cell decreased amount , abnormal
Show

 ZFA:0009316 cardiac muscle cell cardiac muscle cell nuclear chromatin located in cardiac muscle cell nuclear membrane, abnormal
cardiac muscle cell mitochondrion vacuolated , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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