ENSDARG00000103054


Danio rerio

Features
Gene ID: ENSDARG00000103054
  
Biological name :dnm2b
  
Synonyms : dnm2b / dynamin 2b
  
Possible biological names infered from orthology : DNM2 / dynamin 2 / Mus musculus dynamin 2 (Dnm2), transcript variant 5, mRNA. / P39054 / P50570
  
Species: Danio rerio
  
Chr. number: 1
Strand: -1
Band:
Gene start: 58857088
Gene end: 58868306
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000137170
swissprot - A0A0G2KXI9
ZFIN ID - ZDB-GENE-040426-2371
Ensembl - ENSDARG00000103054
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DNM2ENSG00000079805Homo sapiens
 Dnm2ENSMUSG00000033335Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dnm2a / dynamin 2aENSDARG0000006993789
dnm1b / dynamin 1b / DNM1* / P39053* / Q05193* / dynamin 1*ENSDARG0000000928182
dnm1a / dynamin 1a / DNM1* / P39053* / Q05193* / dynamin 1*ENSDARG0000001004282
dnm3a / dynamin 3aENSDARG0000003223878
CABZ01092282.1ENSDARG0000010014549
dnm1l / Q7SXN5 / dynamin 1-like / O00429* / Q8K1M6* / Dynamin-1-like protein *ENSDARG0000001500631
si:dkey-32e23.4ENSDARG0000006315930
mxa / myxovirus (influenza) resistance AENSDARG0000002168821
mxb / myxovirus (influenza) resistance BENSDARG0000000495320
mxe / Q800G5 / myxovirus (influenza virus) resistance E / MX1* / MX2* / P20591* / P20592* / Q9WVP9* / MX dynamin like GTPase 2* / MX dynamin like GTPase 1* / Mus musculus MX dynamin-like GT...ENSDARG0000001442717
mxd / myxovirus (influenza virus) resistance DENSDARG0000002336917
mxg / myxovirus (influenza virus) resistance GENSDARG0000000801917
mxc / Q6DKF0 / myxovirus (influenza virus) resistance C / MX1* / MX2* / Q9WVP9* / P20591* / P20592* / MX dynamin like GTPase 2* / MX dynamin like GTPase 1* / Mus musculus MX dynamin-like GT...ENSDARG0000002478916
mxf / myxovirus (influenza virus) resistance FENSDARG0000002604916
si:dkeyp-110c12.3ENSDARG0000005179514
CABZ01084501.2 / DNM2* / P50570* / dynamin 2*ENSDARG000001133320


Protein motifs (from Interpro)
Interpro ID Name
 IPR000375  Dynamin central domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR022812  Dynamin superfamily
 IPR027188  Dynamin-2
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030381  Dynamin-type guanine nucleotide-binding (G) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000266 mitochondrial fission IBA
 biological_processGO:0003094 glomerular filtration IMP
 biological_processGO:0003374 dynamin family protein polymerization involved in mitochondrial fission IBA
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0032956 regulation of actin cytoskeleton organization IMP
 biological_processGO:0043009 chordate embryonic development IMP
 biological_processGO:0048747 muscle fiber development IMP
 biological_processGO:0061025 membrane fusion IBA
 biological_processGO:0072015 glomerular visceral epithelial cell development IMP
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0031966 mitochondrial membrane IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IBA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0008017 microtubule binding IBA


Pathways (from Reactome)
Pathway description
Gap junction degradation
Formation of annular gap junctions
NOSTRIN mediated eNOS trafficking
MHC class II antigen presentation
Lysosome Vesicle Biogenesis
Golgi Associated Vesicle Biogenesis
Recycling pathway of L1
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000088 YSL YSL edematous , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000473 trunk musculature trunk musculature myofibril decreased size , abnormal
Show

 ZFA:0001094 whole organism whole organism anterior-posterior axis decreased thickness , abnormal
whole organism decreased length , abnormal
whole organism decreased life span , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved , abnormal
post-vent region curved dorsal , abnormal
Show

 ZFA:0001557 pronephric glomerulus pronephric glomerulus podocyte foot morphology , abnormal
Show

 ZFA:0005145 muscle muscle morphology , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr