ENSMUSG00000033335


Mus musculus

Features
Gene ID: ENSMUSG00000033335
  
Biological name :Dnm2
  
Synonyms : Dnm2 / Mus musculus dynamin 2 (Dnm2), transcript variant 5, mRNA. / P39054
  
Possible biological names infered from orthology : dynamin 2 / P50570
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: A3
Gene start: 21424908
Gene end: 21507759
  
Corresponding Affymetrix probe sets: 10583647 (MoGene1.0st)   1423629_at (Mouse Genome 430 2.0 Array)   1425135_a_at (Mouse Genome 430 2.0 Array)   1425136_x_at (Mouse Genome 430 2.0 Array)   1432004_a_at (Mouse Genome 430 2.0 Array)   1432005_at (Mouse Genome 430 2.0 Array)   1437938_x_at (Mouse Genome 430 2.0 Array)   1451057_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000134696
Ensembl peptide - ENSMUSP00000072199
Ensembl peptide - ENSMUSP00000088616
Ensembl peptide - ENSMUSP00000111063
Ensembl peptide - ENSMUSP00000128961
Ensembl peptide - ENSMUSP00000133564
Ensembl peptide - ENSMUSP00000133858
Ensembl peptide - ENSMUSP00000133961
Ensembl peptide - ENSMUSP00000134243
NCBI entrez gene - 13430     See in Manteia.
MGI - MGI:109547
RefSeq - XM_017313129
RefSeq - XM_006509974
RefSeq - XM_006509975
RefSeq - XM_006509976
RefSeq - XM_006509977
RefSeq - XM_006509978
RefSeq - XM_006509979
RefSeq - XM_006509980
RefSeq - XM_006509981
RefSeq - XM_006509982
RefSeq - XM_006509983
RefSeq - XM_006509985
RefSeq - XM_017313125
RefSeq - XM_017313126
RefSeq - XM_017313127
RefSeq - XM_017313128
RefSeq - NM_001039520
RefSeq - NM_001253893
RefSeq - NM_001253894
RefSeq - NM_001357718
RefSeq - NM_001357719
RefSeq - NM_001357721
RefSeq - NM_007871
RefSeq - XM_006509973
RefSeq Peptide - NP_001344650
RefSeq Peptide - NP_031897
RefSeq Peptide - NP_001344648
RefSeq Peptide - NP_001034609
RefSeq Peptide - NP_001240822
RefSeq Peptide - NP_001240823
RefSeq Peptide - NP_001344647
swissprot - F8WIV5
swissprot - P39054
swissprot - G3UZZ3
swissprot - G3X9G4
swissprot - G3UXX2
swissprot - G3UY64
swissprot - Q3T9X3
swissprot - Q3TCR7
Ensembl - ENSMUSG00000033335
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01084501.2ENSDARG00000113332Danio rerio
 dnm2bENSDARG00000103054Danio rerio
 DNM2ENSG00000079805Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dnm1 / P39053 / Dynamin-1 / Q05193*ENSMUSG0000002682580
Dnm3 / Q8BZ98 / Dynamin-3 / Q9UQ16*ENSMUSG0000004026579
Dnm1l / Q8K1M6 / Dynamin-1-like protein / O00429* / dynamin 1 like*ENSMUSG0000002278934
Mx2 / Q9WVP9 / Mus musculus MX dynamin-like GTPase 2 (Mx2), transcript variant 1, mRNA. / MX1* / P20591* / MX dynamin like GTPase 1*ENSMUSG0000002334122
Mx1 / MX dynamin-like GTPase 1 / P20591*ENSMUSG0000000038615


Protein motifs (from Interpro)
Interpro ID Name
 IPR000375  Dynamin central domain
 IPR001401  Dynamin, GTPase domain
 IPR001849  Pleckstrin homology domain
 IPR003130  Dynamin GTPase effector
 IPR011993  PH-like domain superfamily
 IPR019762  Dynamin, GTPase region, conserved site
 IPR020850  GTPase effector domain
 IPR022812  Dynamin superfamily
 IPR027188  Dynamin-2
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030381  Dynamin-type guanine nucleotide-binding (G) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000266 mitochondrial fission IBA
 biological_processGO:0002031 G-protein coupled receptor internalization IEA
 biological_processGO:0003281 ventricular septum development IMP
 biological_processGO:0003374 dynamin family protein polymerization involved in mitochondrial fission IBA
 biological_processGO:0006893 Golgi to plasma membrane transport IEA
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0006898 receptor-mediated endocytosis IEA
 biological_processGO:0006909 phagocytosis IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0009416 response to light stimulus IEA
 biological_processGO:0010592 positive regulation of lamellipodium assembly IEA
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IEA
 biological_processGO:0030516 regulation of axon extension IEA
 biological_processGO:0031623 receptor internalization IEA
 biological_processGO:0033572 transferrin transport IEA
 biological_processGO:0035020 regulation of Rac protein signal transduction IEA
 biological_processGO:0035904 aorta development IMP
 biological_processGO:0042220 response to cocaine IEA
 biological_processGO:0044351 macropinocytosis IEA
 biological_processGO:0045429 positive regulation of nitric oxide biosynthetic process IEA
 biological_processGO:0045807 positive regulation of endocytosis IEA
 biological_processGO:0048812 neuron projection morphogenesis IEA
 biological_processGO:0050766 positive regulation of phagocytosis IEA
 biological_processGO:0060976 coronary vasculature development IMP
 biological_processGO:0061025 membrane fusion IBA
 biological_processGO:0071245 cellular response to carbon monoxide IEA
 biological_processGO:0071481 cellular response to X-ray IEA
 biological_processGO:0071732 cellular response to nitric oxide IEA
 biological_processGO:1900026 positive regulation of substrate adhesion-dependent cell spreading IEA
 biological_processGO:1902856 negative regulation of non-motile cilium assembly IEA
 biological_processGO:1903351 cellular response to dopamine IEA
 biological_processGO:1903358 regulation of Golgi organization IEA
 biological_processGO:1903408 positive regulation of sodium:potassium-exchanging ATPase activity IEA
 biological_processGO:1903526 negative regulation of membrane tubulation IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0001891 phagocytic cup IEA
 cellular_componentGO:0001917 photoreceptor inner segment IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005802 trans-Golgi network IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005905 clathrin-coated pit ISS
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0030054 cell junction ISS
 cellular_componentGO:0030426 growth cone IEA
 cellular_componentGO:0030496 midbody IEA
 cellular_componentGO:0030670 phagocytic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0031966 mitochondrial membrane IBA
 cellular_componentGO:0032587 ruffle membrane IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane ISO
 cellular_componentGO:0045334 clathrin-coated endocytic vesicle IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0008017 microtubule binding IBA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0017124 SH3 domain binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0031749 D2 dopamine receptor binding IEA
 molecular_functionGO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding IEA
 molecular_functionGO:0050699 WW domain binding IEA
 molecular_functionGO:0050998 nitric-oxide synthase binding IEA


Pathways (from Reactome)
Pathway description
Toll Like Receptor 4 (TLR4) Cascade
Gap junction degradation
Formation of annular gap junctions
NOSTRIN mediated eNOS trafficking
MHC class II antigen presentation
Lysosome Vesicle Biogenesis
Golgi Associated Vesicle Biogenesis
Recycling pathway of L1
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000111 cleft palate "congenital fissure of the tissues normally uniting to form the palate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
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Allelic Composition: Adamts6b2b2182Clo/Adamts6b2b2182Clo
Genetic Background: C57BL/6J-Adamts6b2b2182Clo

 MP:0000273 overriding aorta "congenitally mispositioned aorta where the origin straddles the ventral septum and so receives ejected blood from the right ventricle as well as the left." [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cml, J:67826]
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Allelic Composition: Adamts6b2b2182Clo/Adamts6b2b2182Clo
Genetic Background: C57BL/6J-Adamts6b2b2182Clo

 MP:0000284 double outlet right ventricle "both the aorta and the pulmonary trunk originate from the right ventricle, usually in conjunction with a ventricular septal defect" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:67826]
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Allelic Composition: Adamts6b2b2182Clo/Adamts6b2b2182Clo
Genetic Background: C57BL/6J-Adamts6b2b2182Clo

 MP:0000519 hydronephrosis "dilation of the pelvis and calices of one or both kidneys" [J:56641]
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Allelic Composition: Adamts6b2b2182Clo/Adamts6b2b2182Clo
Genetic Background: C57BL/6J-Adamts6b2b2182Clo

 MP:0000747 muscle weakness "loss of muscle strength" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Dnm2tm1.1Ics/Dnm2tm1.1Ics
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0001297 microphthalmia "reduced average size of the eyes" [J:18048]
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Allelic Composition: Adamts6b2b2182Clo/Adamts6b2b2182Clo
Genetic Background: C57BL/6J-Adamts6b2b2182Clo

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Rictortm1.1Mgn/Rictortm1.1Mgn
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac

 MP:0001891 hydroencephaly "excessive accumulation of cerebrospinal fluid in the brain, especially the cerebral ventricles, often leading to increased brain size and other brain trauma" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings, 2003]
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Allelic Composition: Adamts6b2b2182Clo/Adamts6b2b2182Clo
Genetic Background: C57BL/6J-Adamts6b2b2182Clo

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: BcorGt(W096D07)Wrst/Y
Genetic Background: chimera involves: 129S2/SvPas

 MP:0002269 muscular atrophy "a wasting of muscle tissue resulting in a derangement of the muscle fibers; occurs with age, immobilization, weightlessness, malnutrition or denervation" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
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Allelic Composition: Dnm2tm1.1Ics/Dnm2tm1.1Ics
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0002792 abnormal retinal vascularization "malformation or disorganization of the blood vessels supplying the retina" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
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Allelic Composition: Kdrtm2.1Jrt/Kdrtm2.1Jrt,Tg(Cdh5-cre/ERT2)#Ykub/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Dnm1tm2.1Pdc/Dnm1tm2.1Pdc,Dnm2tm1.1Pdc/Dnm2tm1.1Pdc,Kdrtm2.1Jrt/Kdrtm2.1Jrt,Tg(Pax6-cre,GFP)2Pgr/0
Genetic Background: involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ * C57BL/6

 MP:0003084 abnormal skeletal muscle fiber morphology "anomalous structure of the skeletal muscle fibers, the large multinucleated cells that make up the skeletal muscles" [smb:Susan M. Bello, Mouse Genome Informatics Curator, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Dnm2tm1.1Ics/Dnm2tm1.1Ics
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Dnm2tm1.1Ics/Dnm2+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0004231 abnormal calcium ion homeostasis "anomaly in the processes involved in the maintenance of an internal equilibrium of calcium ions within the body or between a cell and its external environment" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Dnm2tm1.1Ics/Dnm2+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0004818 increased skeletal muscle mass "increase in the physical bulk, or total amount of matter contained within skeletal muscle" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Dnm2tm1.1Ics/Dnm2+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0004819 decreased skeletal muscle mass "reduction in the physical bulk, or total amount of matter contained within skeletal muscle" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Dnm2tm1.1Ics/Dnm2+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0005620 abnormal muscle contractility "aberrant ability of a muscle to shorten or to develop increased tension" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Dnm2tm1.1Ics/Dnm2tm1.1Ics
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0005621 abnormal cell physiology "aberration in the vital processes of the cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]
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Allelic Composition: BcorGt(W096D07)Wrst/Y
Genetic Background: chimera involves: 129S2/SvPas

Allelic Composition: Dnm2tm1.1Ics/Dnm2tm1.1Ics
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0006069 abnormal retinal neuronal layer morphology "malformation in any of the neuronal layers that make up the retina, including the ganglion cell, inner plexiform, inner nuclear, outer plexiform, outer nuclear layers, the inner and outer segments" [smb:Susan M Bello, Mouse Genome Informatics Curator, Gray s Anatomy:ISBN 0-914294-08-3]
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Allelic Composition: Kdrtm2.1Jrt/Kdrtm2.1Jrt,Tg(Cdh5-cre/ERT2)#Ykub/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0008528 polycystic kidney "the development of innumerable cysts in the kidneys filled with fluid replacing much of the mass of the kidneys leading to reduction in kidney function and frequently kidney failure" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Adamts6b2b2182Clo/Adamts6b2b2182Clo
Genetic Background: C57BL/6J-Adamts6b2b2182Clo

 MP:0009399 increased skeletal muscle fiber size "increase in the size of the large multinucleated cells that make up the skeletal muscles" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Dnm2tm1.1Ics/Dnm2+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0009400 decreased skeletal muscle fiber size "decrease in the size of the large multinucleated cells that make up the skeletal muscles" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Dnm2tm1.1Ics/Dnm2tm1.1Ics
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Dnm2tm1.1Ics/Dnm2+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0009402 decreased skeletal muscle fiber diameter "decreased width of the cross-sectional distance that extends from one lateral edge of a skeletal muscle fiber, through its center and to the opposite lateral edge" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Dnm2tm1.1Ics/Dnm2+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0009404 centrally nucleated skeletal muscle fibers "cell nuclei are located at a position in the center of the skeletal myofiber, instead of their normal location at the periphery of the fiber; may be indicative of centronuclear myopathy" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Dnm2tm1.1Ics/Dnm2tm1.1Ics
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0009674 decreased birth weight "reduction in average weight at birth compared to controls" [RGD:cur "Rat Genome Database submission"]
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Allelic Composition: Dnm2tm1.1Ics/Dnm2tm1.1Ics
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0010402 ventricular septal defect "abnormal communications between the two lower chambers of the heart, including such defects in the perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular regions" [MESH:C14.240.400.560.540]
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Allelic Composition: Adamts6b2b2182Clo/Adamts6b2b2182Clo
Genetic Background: C57BL/6J-Adamts6b2b2182Clo

 MP:0010418 perimembraneous ventricular septal defect "abnormal communications between the two lower chambers of the heart, occurring in the membranous septum with defects in the adjacent muscular portion of the septum; it is generally located in the LV outflow tract just below the aortic valve, associated with pouches or aneurysms of the septal leaflet of the tricuspid valve, which may partially or completely close the defect; an LV-to-RA shunt may also be associated with this defect" [http://emedicine.medscape.com]
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Allelic Composition: Adamts6b2b2182Clo/Adamts6b2b2182Clo
Genetic Background: C57BL/6J-Adamts6b2b2182Clo

 MP:0010420 muscular ventricular septal defect "abnormal communications between the two lower chambers of the heart, involving the muscular septum and often occurring as multiple communications, and includes central muscular or midmuscular, apical, or marginal communications when the defect is along the RV-septal junction; any single defect observed from the LV aspect may have several openings on the RV aspect" [http://emedicine.medscape.com]
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Allelic Composition: Adamts6b2b2182Clo/Adamts6b2b2182Clo
Genetic Background: C57BL/6J-Adamts6b2b2182Clo

 MP:0010466 vascular ring "the trachea and esophagus are completely encircled by connected segments of the aortic arch and its branches" [http://emedicine.medscape.com]
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Allelic Composition: Adamts6b2b2182Clo/Adamts6b2b2182Clo
Genetic Background: C57BL/6J-Adamts6b2b2182Clo

 MP:0010541 aorta hypoplasia "underdevelopment or reduced size of the main trunk of the systemic arterial system that originates from the base of the left ventricle of the heart and extends to the abdomen at the point where it branches into the common iliac arteries, usually due to reduced cell number" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Adamts6b2b2182Clo/Adamts6b2b2182Clo
Genetic Background: C57BL/6J-Adamts6b2b2182Clo

 MP:0011084 partial lethality at weaning "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms at weaning age" [MGI:csmith]
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Allelic Composition: Dnm2tm1.1Ics/Dnm2tm1.1Ics
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0011088 partial neonatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith]
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Allelic Composition: Dnm2tm1.1Ics/Dnm2tm1.1Ics
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
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Allelic Composition: BcorGt(W096D07)Wrst/Y
Genetic Background: chimera involves: 129S2/SvPas

 MP:0012260 encephalomeningocele "hernial protrusion of the brain and its meninges through an opening or defect in the skull, most often occuring in the occipital region" [ISBN:0-683-40008-8]
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Allelic Composition: Adamts6b2b2182Clo/Adamts6b2b2182Clo
Genetic Background: C57BL/6J-Adamts6b2b2182Clo

 MP:0013293 embryonic lethality prior to tooth bud stage "death prior to the appearance of tooth buds (Mus: E12-E12.5)" [MGI:smb]
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Allelic Composition: Dbn1tm1b(KOMP)Wtsi/Dbn1+
Genetic Background: C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Bay

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000003033 Ap1m1 / P35585 / AP-1 complex subunit mu-1 / Q9BXS5* / adaptor related protein complex 1 mu 1 subunit*  / complex / reaction
 ENSMUSG00000003309 Ap1m2 / adaptor related protein complex 1 mu 2 subunit / Q9Y6Q5*  / complex / reaction
 ENSMUSG00000009090 Ap1b1 / O35643 / Mus musculus adaptor protein complex AP-1, beta 1 subunit (Ap1b1), transcript variant 4, mRNA. / Q10567* / adaptor related protein complex 1 beta 1 subunit*  / complex / reaction
 ENSMUSG00000007655 Cav1 / P49817 / Caveolin-1 / Q03135*  / complex / reaction
 ENSMUSG00000029684 Wasl / Q91YD9 / Wiskott-Aldrich syndrome-like (human) / O00401* / Wiskott-Aldrich syndrome like*  / complex / reaction
 ENSMUSG00000028488 Q62420 / Sh3gl2 / SH3-domain GRB2-like 2 / Q99962* / SH3 domain containing GRB2 like 2, endophilin A1*  / complex
 ENSMUSG00000034738 Q6WKZ7 / Nostrin / Q8IVI9* / nitric oxide synthase trafficking*  / reaction / complex
 ENSMUSG00000031731 Ap1g1 / P22892 / AP-1 complex subunit gamma-1 / O43747* / adaptor related protein complex 1 gamma 1 subunit*  / complex / reaction
 ENSMUSG00000031367 Ap1s2 / Q9DB50 / AP-1 complex subunit sigma-2 / P56377* / adaptor related protein complex 1 sigma 2 subunit*  / complex / reaction
 ENSMUSG00000028978 Nos3 / P70313 / Nitric oxide synthase, endothelial / P29474* / nitric oxide synthase 3*  / complex / reaction
 ENSMUSG00000024610 Cd74 / P04441 / CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) / P04233* / CD74 molecule*  / complex / reaction
 ENSMUSG00000001173 Ocrl / Q6NVF0 / Inositol polyphosphate 5-phosphatase OCRL-1 / Q01968* / OCRL, inositol polyphosphate-5-phosphatase*  / reaction / complex
 ENSMUSG00000060586 H2-Eb1 / Q9GIY3* / P01911* / P04229* / Q29974* / Q30154* / HLA-DRB5* / HLA-DRB1* / major histocompatibility complex, class II, DR beta 1* / major histocompatibility complex, class II, DR beta 5*  / complex / reaction
 ENSMUSG00000036594 H2-Aa / P14434 / H-2 class II histocompatibility antigen, A-B alpha chain / P01909* / P01906* / HLA-DQA2* / HLA-DQA1* / major histocompatibility complex, class II, DQ alpha 2* / major hist...  / reaction / complex
 ENSMUSG00000067341 H2-Eb2 / Q9GIY3* / P01911* / P04229* / Q29974* / Q30154* / HLA-DRB5* / HLA-DRB1* / major histocompatibility complex, class II, DR beta 1* / major histocompatibility complex, class II, DR beta 5*  / complex / reaction
 ENSMUSG00000004849 Ap1s1 / P61967 / AP-1 complex subunit sigma-1A / P61966* / adaptor related protein complex 1 sigma 1 subunit*  / reaction / complex
 ENSMUSG00000023805 Synj2 / Q9D2G5 / Synaptojanin-2 / O15056*  / complex / reaction
 ENSMUSG00000073421 H2-Ab1 / P14483 / histocompatibility 2, class II antigen A, beta 1 / P05538* / HLA-DQB1* / HLA-DQB2* / major histocompatibility complex, class II, DQ beta 1* / major histocompatibility comp...  / reaction / complex
 ENSMUSG00000054702 Ap1s3 / Q7TN05 / AP-1 complex subunit sigma-3 / Q96PC3* / adaptor related protein complex 1 sigma 3 subunit*  / reaction / complex
 ENSMUSG00000033335 Dnm2 / P39054 / Mus musculus dynamin 2 (Dnm2), transcript variant 5, mRNA. / P50570* / dynamin 2*  / reaction






 

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