ENSMUSG00000023341


Mus musculus

Features
Gene ID: ENSMUSG00000023341
  
Biological name :Mx2
  
Synonyms : Mus musculus MX dynamin-like GTPase 2 (Mx2), transcript variant 1, mRNA. / Mx2 / Q9WVP9
  
Possible biological names infered from orthology : MX1 / MX dynamin like GTPase 1 / P20591
  
Species: Mus musculus
  
Chr. number: 16
Strand: 1
Band: C4
Gene start: 97535308
Gene end: 97560900
  
Corresponding Affymetrix probe sets: 10437224 (MoGene1.0st)   1419676_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000024112
Ensembl peptide - ENSMUSP00000140229
Ensembl peptide - ENSMUSP00000141038
NCBI entrez gene - 17858     See in Manteia.
MGI - MGI:97244
RefSeq - NM_013606
RefSeq Peptide - NP_038634
swissprot - Q9WVP9
Ensembl - ENSMUSG00000023341
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mxcENSDARG00000024789Danio rerio
 mxeENSDARG00000014427Danio rerio
 MX1ENSGALG00000016142Gallus gallus
 MX1ENSG00000157601Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mx1 / MX dynamin-like GTPase 1 / P20591*ENSMUSG0000000038646
Dnm1 / P39053 / Dynamin-1 / Q05193*ENSMUSG0000002682529
Dnm3 / Q8BZ98 / Dynamin-3 / Q9UQ16*ENSMUSG0000004026529
Dnm2 / P39054 / Mus musculus dynamin 2 (Dnm2), transcript variant 5, mRNA. / P50570* / dynamin 2*ENSMUSG0000003333529
Dnm1l / Q8K1M6 / Dynamin-1-like protein / O00429* / dynamin 1 like*ENSMUSG0000002278926


Protein motifs (from Interpro)
Interpro ID Name
 IPR000375  Dynamin central domain
 IPR001401  Dynamin, GTPase domain
 IPR003130  Dynamin GTPase effector
 IPR019762  Dynamin, GTPase region, conserved site
 IPR020850  GTPase effector domain
 IPR022812  Dynamin superfamily
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030381  Dynamin-type guanine nucleotide-binding (G) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000266 mitochondrial fission IBA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0003374 dynamin family protein polymerization involved in mitochondrial fission IBA
 biological_processGO:0009615 response to virus IDA
 biological_processGO:0034340 response to type I interferon IDA
 biological_processGO:0045071 negative regulation of viral genome replication IDA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0051607 defense response to virus IBA
 biological_processGO:0061025 membrane fusion IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0031966 mitochondrial membrane IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IBA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0008017 microtubule binding IBA


Pathways (from Reactome)
Pathway description
ISG15 antiviral mechanism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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