ENSDARG00000014427


Danio rerio

Features
Gene ID: ENSDARG00000014427
  
Biological name :mxe
  
Synonyms : mxe / myxovirus (influenza virus) resistance E / Q800G5
  
Possible biological names infered from orthology : Mus musculus MX dynamin-like GTPase 2 (Mx2), transcript variant 1, mRNA. / MX1 / MX2 / MX dynamin like GTPase 1 / MX dynamin like GTPase 2 / P20591 / P20592 / Q9WVP9
  
Species: Danio rerio
  
Chr. number: 9
Strand: -1
Band:
Gene start: 32824639
Gene end: 32837860
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000118741
NCBI entrez gene - 337663     See in Manteia.
RefSeq - XM_005167664
RefSeq Peptide - NP_878287
swissprot - Q800G5
ZFIN ID - ZDB-GENE-030131-9609
Ensembl - ENSDARG00000014427
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MX1ENSGALG00000016142Gallus gallus
 MX1ENSG00000157601Homo sapiens
 MX2ENSG00000183486Homo sapiens
 Mx1ENSMUSG00000000386Mus musculus
 Mx2ENSMUSG00000023341Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mxc / Q6DKF0 / myxovirus (influenza virus) resistance C / MX1* / MX2* / Q9WVP9* / P20591* / P20592* / MX dynamin like GTPase 2* / MX dynamin like GTPase 1* / Mus musculus MX dynamin-like GT...ENSDARG0000002478976
mxa / myxovirus (influenza) resistance AENSDARG0000002168849
mxb / myxovirus (influenza) resistance BENSDARG0000000495348
mxg / myxovirus (influenza virus) resistance GENSDARG0000000801944
mxd / myxovirus (influenza virus) resistance DENSDARG0000002336943
mxf / myxovirus (influenza virus) resistance FENSDARG0000002604941
si:dkeyp-110c12.3ENSDARG0000005179541
dnm2a / dynamin 2aENSDARG0000006993728
dnm3a / dynamin 3aENSDARG0000003223828
dnm1l / Q7SXN5 / dynamin 1-like / O00429* / Q8K1M6* / Dynamin-1-like protein *ENSDARG0000001500627
dnm1b / dynamin 1b / DNM1* / P39053* / Q05193* / dynamin 1*ENSDARG0000000928127
dnm1a / dynamin 1a / DNM1* / P39053* / Q05193* / dynamin 1*ENSDARG0000001004227
si:dkey-32e23.4ENSDARG0000006315926
CABZ01092282.1ENSDARG0000010014517
dnm2b / dynamin 2b / DNM2* / P50570* / dynamin 2*ENSDARG0000010305412
CABZ01084501.2 / DNM2* / P50570* / dynamin 2*ENSDARG0000011333210


Protein motifs (from Interpro)
Interpro ID Name
 IPR000375  Dynamin central domain
 IPR001401  Dynamin, GTPase domain
 IPR003130  Dynamin GTPase effector
 IPR019762  Dynamin, GTPase region, conserved site
 IPR020850  GTPase effector domain
 IPR022812  Dynamin superfamily
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030381  Dynamin-type guanine nucleotide-binding (G) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000266 mitochondrial fission IBA
 biological_processGO:0003374 dynamin family protein polymerization involved in mitochondrial fission IBA
 biological_processGO:0009615 response to virus IDA
 biological_processGO:0045087 innate immune response IBA
 biological_processGO:0051607 defense response to virus IBA
 biological_processGO:0061025 membrane fusion IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0031966 mitochondrial membrane IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IBA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0008017 microtubule binding IBA


Pathways (from Reactome)
Pathway description
ISG15 antiviral mechanism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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