ENSDARG00000069958


Danio rerio

Features
Gene ID: ENSDARG00000069958
  
Biological name :sh2b3
  
Synonyms : sh2b3 / SH2B adaptor protein 3
  
Possible biological names infered from orthology : O09039 / Q9UQQ2 / SH2B adapter protein 3
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 9556943
Gene end: 9625459
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000093012
Ensembl peptide - ENSDARP00000121820
swissprot - F1Q4S0
swissprot - F6P9Y8
ZFIN ID - ZDB-GENE-041210-359
Ensembl - ENSDARG00000069958
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SH2B3ENSGALG00000004610Gallus gallus
 SH2B3ENSG00000111252Homo sapiens
 Sh2b3ENSMUSG00000042594Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SH2B2 / SH2B adaptor protein 2 / Q9JID9*ENSDARG0000009042129
sh2b1 / SH2B adaptor protein 1 / Q91ZM2* / Q9NRF2* / SH2B adapter protein 1 *ENSDARG0000005767926


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR015012  Phenylalanine zipper
 IPR030522  SH2B adapter protein 3
 IPR030523  SH2B adapter protein
 IPR035059  SH2B3, SH2 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0009967 positive regulation of signal transduction IEA
 biological_processGO:0030097 hemopoiesis IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0035591 signaling adaptor activity IEA


Pathways (from Reactome)
Pathway description
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000104808 jak2a / Janus kinase 2a / JAK2* / O60674* / Janus kinase 2*  / reaction / complex
 ENSDARG00000018882 jak2b / Janus kinase 2b / JAK2* / O60674* / Janus kinase 2*  / reaction / complex






 

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