ENSDARG00000057679


Danio rerio

Features
Gene ID: ENSDARG00000057679
  
Biological name :sh2b1
  
Synonyms : sh2b1 / SH2B adaptor protein 1
  
Possible biological names infered from orthology : Q91ZM2 / Q9NRF2 / SH2B adapter protein 1
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 15358459
Gene end: 15392466
  
Corresponding Affymetrix probe sets: Dr.10574.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000078411
Ensembl peptide - ENSDARP00000118660
Ensembl peptide - ENSDARP00000115931
NCBI entrez gene - 558152     See in Manteia.
RefSeq - XM_017354352
RefSeq - XM_017354353
RefSeq Peptide - NP_001103925
swissprot - E9QI81
swissprot - A2RUZ0
ZFIN ID - ZDB-GENE-070209-188
Ensembl - ENSDARG00000057679
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SH2B1ENSG00000178188Homo sapiens
 Sh2b1ENSMUSG00000030733Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SH2B2 / SH2B adaptor protein 2 / Q9JID9*ENSDARG0000009042123
sh2b3 / SH2B adaptor protein 3 / O09039* / Q9UQQ2* / SH2B adapter protein 3 *ENSDARG0000006995817


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR015012  Phenylalanine zipper
 IPR030521  SH2B adapter protein 1
 IPR030523  SH2B adapter protein
 IPR035057  SH2B1, SH2 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0009967 positive regulation of signal transduction IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0035591 signaling adaptor activity IEA


Pathways (from Reactome)
Pathway description
Prolactin receptor signaling
Growth hormone receptor signaling
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000018882 jak2b / Janus kinase 2b / JAK2* / O60674* / Janus kinase 2*  / complex / reaction
 ENSDARG00000104808 jak2a / Janus kinase 2a / JAK2* / O60674* / Janus kinase 2*  / complex / reaction
 ENSDARG00000038185 gh1 / growth hormone 1 / Gh* / GH2* / CSH2* / CSH1* / CSHL1* / P01242* / Q14406* / P0DML3* / P0DML2* / P01241* / P06880* / Somatotropin * / growth hormone 2* / chorionic somatomammotropin h...  / reaction / complex






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr