ENSDARG00000070453


Danio rerio

Features
Gene ID: ENSDARG00000070453
  
Biological name :gch1
  
Synonyms : gch1 / GTP cyclohydrolase 1
  
Possible biological names infered from orthology : P30793 / Q05915
  
Species: Danio rerio
  
Chr. number: 17
Strand: -1
Band:
Gene start: 15121977
Gene end: 15149275
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000124435
Ensembl peptide - ENSDARP00000094181
Ensembl peptide - ENSDARP00000151543
NCBI entrez gene - 100192219     See in Manteia.
swissprot - E7FGQ8
swissprot - F8W3B2
ZFIN ID - ZDB-GENE-070720-5
Ensembl - ENSDARG00000070453
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GCH1ENSGALG00000012200Gallus gallus
 GCH1ENSG00000131979Homo sapiens
 Gch1ENSMUSG00000037580Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gch2 / GTP cyclohydrolase 2ENSDARG0000009910163
CU464134.2 / GCH1* / P30793* / GTP cyclohydrolase 1*ENSDARG0000011315813


Protein motifs (from Interpro)
Interpro ID Name
 IPR001474  GTP cyclohydrolase I
 IPR018234  GTP cyclohydrolase I, conserved site
 IPR020602  GTP cyclohydrolase I domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006729 tetrahydrobiopterin biosynthetic process IBA
 biological_processGO:0046654 tetrahydrofolate biosynthetic process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003934 GTP cyclohydrolase I activity IEA
 molecular_functionGO:0005525 GTP binding IBA
 molecular_functionGO:0008270 zinc ion binding IBA


Pathways (from Reactome)
Pathway description
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000070453 gch1 / GTP cyclohydrolase 1 / P30793* / Q05915*  / complex
 ENSDARG00000098588 gchfr / Q6PBT6 / GTP cyclohydrolase I feedback regulator / P30047*  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr