ENSDARG00000098588


Danio rerio

Features
Gene ID: ENSDARG00000098588
  
Biological name :gchfr
  
Synonyms : gchfr / GTP cyclohydrolase I feedback regulator / Q6PBT6
  
Possible biological names infered from orthology : GTP cyclohydrolase 1 feedback regulatory protein / P30047 / P99025
  
Species: Danio rerio
  
Chr. number: 17
Strand: 1
Band:
Gene start: 1063988
Gene end: 1069194
  
Corresponding Affymetrix probe sets: Dr.12454.1.S1_at (Zebrafish Array)   NM_200762_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000135960
NCBI entrez gene - 393735     See in Manteia.
RefSeq - XM_005158967
RefSeq - NM_200762
RefSeq Peptide - NP_957056
swissprot - Q6PBT6
ZFIN ID - ZDB-GENE-040426-1731
Ensembl - ENSDARG00000098588
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GCHFRENSGALG00000032239Gallus gallus
 GCHFRENSG00000137880Homo sapiens
 GchfrENSMUSG00000046814Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009112  GTP cyclohydrolase I, feedback regulatory protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009890 negative regulation of biosynthetic process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031965 nuclear membrane IEA


Pathways (from Reactome)
Pathway description
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000070453 gch1 / GTP cyclohydrolase 1 / P30793* / Q05915*  / complex / reaction
 ENSDARG00000098588 gchfr / Q6PBT6 / GTP cyclohydrolase I feedback regulator / P30047*  / reaction / complex






 

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contact: otassy@igbmc.fr