ENSDARG00000070620


Danio rerio

Features
Gene ID: ENSDARG00000070620
  
Biological name :grin2db
  
Synonyms : glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b / grin2db
  
Possible biological names infered from orthology : glutamate ionotropic receptor NMDA type subunit 2D / Glutamate receptor ionotropic, NMDA 2D / GRIN2D / O15399 / Q03391
  
Species: Danio rerio
  
Chr. number: 16
Strand: -1
Band:
Gene start: 13179146
Gene end: 13388821
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000094658
Ensembl peptide - ENSDARP00000114258
swissprot - E7F3Z4
swissprot - E9QBK8
ZFIN ID - ZDB-GENE-100920-7
Ensembl - ENSDARG00000070620
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GRIN2DENSG00000105464Homo sapiens
 Grin2dENSMUSG00000002771Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
grin2da / glutamate receptor, ionotropic, N-methyl D-aspartate 2D, a / Q03391* / GRIN2D* / O15399* / Glutamate receptor ionotropic, NMDA 2D * / glutamate ionotropic receptor NMDA type subunit 2D*ENSDARG0000008620765
grin2ca / glutamate receptor, ionotropic, N-methyl D-aspartate 2Ca / Q14957* / GRIN2C* / Q01098* / Glutamate receptor ionotropic, NMDA 2C * / glutamate ionotropic receptor NMDA type subunit 2C*ENSDARG0000007814928
grin2cb / glutamate receptor, ionotropic, N-methyl D-aspartate 2Cb / Q14957* / GRIN2C* / Q01098* / Glutamate receptor ionotropic, NMDA 2C * / glutamate ionotropic receptor NMDA type subunit 2C*ENSDARG0000007756027
grin2aa / glutamate receptor, ionotropic, N-methyl D-aspartate 2A, a / Q12879* / GRIN2A* / P35436* / Glutamate receptor ionotropic, NMDA 2A * / glutamate ionotropic receptor NMDA type subunit 2A*ENSDARG0000003449326
LO018552.1 / GRIN2B* / Q13224* / glutamate ionotropic receptor NMDA type subunit 2B*ENSDARG0000007934826
grin2ab / glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b / Q12879* / GRIN2A* / P35436* / Glutamate receptor ionotropic, NMDA 2A * / glutamate ionotropic receptor NMDA type subunit 2A*ENSDARG0000007054326
grin2bb / glutamate receptor, ionotropic, N-methyl D-aspartate 2B, genome duplicate b / GRIN2B* / Q13224* / glutamate receptor, ionotropic, NMDA2B (epsilon 2)* / glutamate ionotropic recept...ENSDARG0000003037626
grin3bb / glutamate receptor, ionotropic, N-methyl-D-aspartate 3Bb / Q91ZU9* / GRIN3B* / O60391* / Glutamate receptor ionotropic, NMDA 3B * / glutamate ionotropic receptor NMDA type subunit 3B*ENSDARG0000009866712
grin3ba / glutamate receptor, ionotropic, N-methyl-D-aspartate 3Ba / Q91ZU9* / GRIN3B* / O60391* / Glutamate receptor ionotropic, NMDA 3B * / glutamate ionotropic receptor NMDA type subunit 3B*ENSDARG0000000536412
grin3a / glutamate receptor, ionotropic, N-methyl-D-aspartate 3A / Q8TCU5* / glutamate ionotropic receptor NMDA type subunit 3A*ENSDARG0000007580211
grin1b / glutamate receptor, ionotropic, N-methyl D-aspartate 1b / GRIN1* / P35438* / Q05586* / Glutamate receptor ionotropic, NMDA 1 * / glutamate ionotropic receptor NMDA type subunit 1*ENSDARG0000002572810
grin1a / glutamate receptor, ionotropic, N-methyl D-aspartate 1a / GRIN1* / P35438* / Q05586* / Glutamate receptor ionotropic, NMDA 1 * / glutamate ionotropic receptor NMDA type subunit 1*ENSDARG0000002782810
grik5 / glutamate receptor, ionotropic, kainate 5 / Q16478* / Q61626* / glutamate ionotropic receptor kainate type subunit 5*ENSDARG0000010144910
GRIK2 / glutamate ionotropic receptor kainate type subunit 2 / P39087* / Q13002* / Glutamate receptor ionotropic, kainate 2 *ENSDARG000001137719
grid1a / glutamate receptor, ionotropic, delta 1a / GRID1* / Q61627* / Q9ULK0* / Glutamate receptor ionotropic, delta-1 * / glutamate ionotropic receptor delta type subunit 1*ENSDARG000000745839
grik1a / glutamate receptor, ionotropic, kainate 1a / GRIK1* / P39086* / glutamate ionotropic receptor kainate type subunit 1* / Mus musculus glutamate receptor, ionotropic, kainate 1 (Grik...ENSDARG000000691399
gria2a / glutamate receptor, ionotropic, AMPA 2a / GRIA2* / P42262* / glutamate receptor 2 isoform 3 * / glutamate ionotropic receptor AMPA type subunit 2*ENSDARG000000701739
gria3a / glutamate receptor, ionotropic, AMPA 3a / GRIA3* / P42263* / Q9Z2W9* / glutamate ionotropic receptor AMPA type subunit 3* / Mus musculus glutamate receptor, ionotropic, AMPA3 (alph...ENSDARG000000327379
grik1b / glutamate receptor, ionotropic, kainate 1b / GRIK1* / P39086* / glutamate ionotropic receptor kainate type subunit 1* / Mus musculus glutamate receptor, ionotropic, kainate 1 (Grik...ENSDARG000000406279
GRIK3 / glutamate ionotropic receptor kainate type subunit 3 / Q13003*ENSDARG000000777159


Protein motifs (from Interpro)
Interpro ID Name
 IPR001320  Ionotropic glutamate receptor
 IPR001508  Ionotropic glutamate receptor, metazoa
 IPR001828  Receptor, ligand binding region
 IPR019594  Ionotropic glutamate receptor, L-glutamate and glycine-binding domain
 IPR028082  Periplasmic binding protein-like I


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0035235 ionotropic glutamate receptor signaling pathway IEA
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004970 ionotropic glutamate receptor activity IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005234 extracellularly glutamate-gated ion channel activity IEA


Pathways (from Reactome)
Pathway description
Unblocking of NMDA receptor, glutamate binding and activation
CREB phosphorylation through the activation of CaMKII
Ras activation upon Ca2+ influx through NMDA receptor
RAF/MAP kinase cascade
Synaptic adhesion-like molecules


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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