ENSDARG00000071494


Danio rerio

Features
Gene ID: ENSDARG00000071494
  
Biological name :fshr
  
Synonyms : follicle stimulating hormone receptor / fshr
  
Possible biological names infered from orthology : P23945 / P35378
  
Species: Danio rerio
  
Chr. number: 12
Strand: 1
Band:
Gene start: 24738962
Gene end: 24770190
  
Corresponding Affymetrix probe sets: Dr.24986.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000096529
NCBI entrez gene - 195820     See in Manteia.
RefSeq - NM_001001812
RefSeq Peptide - NP_001001812
swissprot - F1R4X9
ZFIN ID - ZDB-GENE-020423-5
Ensembl - ENSDARG00000071494
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FSHRENSGALG00000009100Gallus gallus
 FSHRENSG00000170820Homo sapiens
 FshrENSMUSG00000032937Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
lhcgr / luteinizing hormone/choriogonadotropin receptor / P22888* / P30730* / AC073082.1* / Lutropin-choriogonadotropic hormone receptor *ENSDARG0000002608148
tshr / thyroid stimulating hormone receptor / P16473*ENSDARG0000003719547
lgr4 / E7FE13 / leucine-rich repeat containing G protein-coupled receptor 4 / A2ARI4* / Q9BXB1*ENSDARG0000006054224
rxfp2b / relaxin/insulin-like family peptide receptor 2b / RXFP2* / Q91ZZ5* / Q8WXD0* / Relaxin receptor 2 * / relaxin/insulin like family peptide receptor 2*ENSDARG0000001966019
rxfp1 / relaxin/insulin-like family peptide receptor 1 / Q6R6I7* / Q9HBX9* / Relaxin receptor 1 *ENSDARG0000009007119
rxfp2a / relaxin/insulin-like family peptide receptor 2a / RXFP2* / Q91ZZ5* / Q8WXD0* / Relaxin receptor 2 * / relaxin/insulin like family peptide receptor 2*ENSDARG0000003282018
rxfp2l / relaxin/insulin-like family peptide receptor 2, likeENSDARG0000006873118


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR001611  Leucine-rich repeat
 IPR002131  Glycoprotein hormone receptor family
 IPR002272  Follicle stimulating hormone receptor
 IPR002274  Thyrotropin receptor
 IPR017452  GPCR, rhodopsin-like, 7TM
 IPR026906  Leucine rich repeat 5
 IPR032675  Leucine-rich repeat domain superfamily
 IPR034298  TSH/LHCG/FSH receptor


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001541 ovarian follicle development IMP
 biological_processGO:0001545 primary ovarian follicle growth IBA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway IBA
 biological_processGO:0007190 activation of adenylate cyclase activity IBA
 biological_processGO:0007283 spermatogenesis IGI
 biological_processGO:0008584 male gonad development IMP
 biological_processGO:0008585 female gonad development IMP
 biological_processGO:0009755 hormone-mediated signaling pathway IBA
 biological_processGO:0038194 thyroid-stimulating hormone signaling pathway IEA
 biological_processGO:0042699 follicle-stimulating hormone signaling pathway IEA
 biological_processGO:0045670 regulation of osteoclast differentiation IBA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004963 follicle-stimulating hormone receptor activity IDA
 molecular_functionGO:0004996 thyroid-stimulating hormone receptor activity IEA
 molecular_functionGO:0008528 G-protein coupled peptide receptor activity IBA
 molecular_functionGO:0016500 protein-hormone receptor activity IEA


Pathways (from Reactome)
Pathway description
Hormone ligand-binding receptors
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000242 male organism male organism increased amount , abnormal
Show

 ZFA:0000303 female organism female organism female sterile , abnormal
female organism decreased amount , abnormal
female organism sterile , abnormal
Show

 ZFA:0000403 ovary ovary decreased size , abnormal
Show

 ZFA:0000598 testis testis immature , abnormal
testis growth decreased process quality , abnormal
testis decreased amount , abnormal
Show

 ZFA:0001094 whole organism whole organism biological sex , abnormal
Show

 ZFA:0001263 ovarian follicle stage I ovarian follicle stage I immature , abnormal
ovarian follicle stage I decreased size , abnormal
Show

 ZFA:0001264 ovarian follicle stage IV ovarian follicle stage IV absent , abnormal
Show

 ZFA:0001265 ovarian follicle stage II ovarian follicle stage II absent , abnormal
Show

 ZFA:0001266 ovarian follicle stage III ovarian follicle stage III absent , abnormal
Show

 ZFA:0009016 germ line cell germ line cell decreased size , abnormal
germ line cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr