ENSDARG00000074301


Danio rerio

Features
Gene ID: ENSDARG00000074301
  
Biological name :cth
  
Synonyms : cth / cystathionase (cystathionine gamma-lyase)
  
Possible biological names infered from orthology : cystathionine gamma-lyase / P32929 / Q8VCN5
  
Species: Danio rerio
  
Chr. number: 6
Strand: -1
Band:
Gene start: 37409558
Gene end: 37422841
  
Corresponding Affymetrix probe sets: Dr.3560.1.A1_at (Zebrafish Array)   NM_212604_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000117293
NCBI entrez gene - 322055     See in Manteia.
RefSeq - NM_212604
RefSeq Peptide - NP_997769
swissprot - F1QPF7
ZFIN ID - ZDB-GENE-030131-774
Ensembl - ENSDARG00000074301
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CTHENSGALG00000011331Gallus gallus
 CTHENSG00000116761Homo sapiens
 CthENSMUSG00000028179Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cthl / cystathionase (cystathionine gamma-lyase), like / CTH* / Q8VCN5* / P32929* / cystathionine gamma-lyase*ENSDARG0000003220682


Protein motifs (from Interpro)
Interpro ID Name
 IPR000277  Cys/Met metabolism, pyridoxal phosphate-dependent enzyme
 IPR015421  Pyridoxal phosphate-dependent transferase, major domain
 IPR015422  Pyridoxal phosphate-dependent transferase domain 1
 IPR015424  Pyridoxal phosphate-dependent transferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0019343 cysteine biosynthetic process via cystathionine IBA
 biological_processGO:0019346 transsulfuration IBA
 biological_processGO:0071266 "de novo" L-methionine biosynthetic process IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003962 cystathionine gamma-synthase activity IBA
 molecular_functionGO:0004123 cystathionine gamma-lyase activity IBA
 molecular_functionGO:0030170 pyridoxal phosphate binding IBA


Pathways (from Reactome)
Pathway description
Degradation of cysteine and homocysteine
Cysteine formation from homocysteine


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000074301 cth / cystathionase (cystathionine gamma-lyase) / P32929* / Q8VCN5* / cystathionine gamma-lyase*  / complex






 

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contact: otassy@igbmc.fr