ENSGALG00000011331


Gallus gallus

Features
Gene ID: ENSGALG00000011331
  
Biological name :CTH
  
Synonyms : CTH / cystathionine gamma-lyase
  
Possible biological names infered from orthology : P32929 / Q8VCN5
  
Species: Gallus gallus
  
Chr. number: 8
Strand: 1
Band:
Gene start: 29152909
Gene end: 29168321
  
Corresponding Affymetrix probe sets: Gga.2872.1.S1_at (Chicken Array)   GgaAffx.23528.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000018469
Ensembl peptide - ENSGALP00000052545
NCBI entrez gene - 424716     See in Manteia.
RefSeq - XM_422542
swissprot - A0A1D5PIB2
swissprot - E1BYF1
Ensembl - ENSGALG00000011331
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cthENSDARG00000074301Danio rerio
 cthlENSDARG00000032206Danio rerio
 CTHENSG00000116761Homo sapiens
 CthENSMUSG00000028179Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000277  Cys/Met metabolism, pyridoxal phosphate-dependent enzyme
 IPR015421  Pyridoxal phosphate-dependent transferase, major domain
 IPR015422  Pyridoxal phosphate-dependent transferase domain 1
 IPR015424  Pyridoxal phosphate-dependent transferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0018272 protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine IEA
 biological_processGO:0019343 cysteine biosynthetic process via cystathionine IEA
 biological_processGO:0019344 cysteine biosynthetic process IEA
 biological_processGO:0019346 transsulfuration IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0044524 protein sulfhydration IEA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IEA
 biological_processGO:0051289 protein homotetramerization IEA
 biological_processGO:0070814 hydrogen sulfide biosynthetic process IEA
 biological_processGO:0071266 "de novo" L-methionine biosynthetic process IBA
 biological_processGO:1904831 positive regulation of aortic smooth muscle cell differentiation IEA
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEA
 biological_processGO:2001234 negative regulation of apoptotic signaling pathway IEA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003962 cystathionine gamma-synthase activity IBA
 molecular_functionGO:0004123 cystathionine gamma-lyase activity IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0044540 L-cystine L-cysteine-lyase (deaminating) IEA


Pathways (from Reactome)
Pathway description
Degradation of cysteine and homocysteine
Cysteine formation from homocysteine


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000011331 CTH / cystathionine gamma-lyase / P32929* / Q8VCN5*  / complex






 

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