ENSDARG00000074634


Danio rerio

Features
Gene ID: ENSDARG00000074634
  
Biological name :keap1b
  
Synonyms : keap1b / kelch-like ECH-associated protein 1b
  
Possible biological names infered from orthology : KEAP1 / kelch like ECH associated protein 1 / Q14145 / Q9Z2X8
  
Species: Danio rerio
  
Chr. number: 6
Strand: -1
Band:
Gene start: 131998
Gene end: 138603
  
Corresponding Affymetrix probe sets: Dr.11210.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000147759
Ensembl peptide - ENSDARP00000124136
Ensembl peptide - ENSDARP00000124228
NCBI entrez gene - 100003679     See in Manteia.
RefSeq - NM_001113477
RefSeq - XM_005168685
RefSeq - XM_021476739
RefSeq Peptide - NP_001106948
swissprot - A9CP01
ZFIN ID - ZDB-GENE-080508-1
Ensembl - ENSDARG00000074634
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KEAP1ENSG00000079999Homo sapiens
 Keap1ENSMUSG00000003308Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
keap1a / kelch-like ECH-associated protein 1aENSDARG0000001613251
klhl17 / kelch-like family member 17 / Q6TDP3* / Q6TDP4* / Plekhn1* / Kelch-like protein 17 *ENSDARG0000003732435
klhl20 / kelch-like family member 20 / Q8VCK5* / Q9Y2M5* / Kelch-like protein 20 *ENSDARG0000003880135
klhl18 / kelch-like family member 18 / O94889*ENSDARG0000000430634
klhl3 / kelch-like family member 3 / E0CZ16* / Q9UH77* / Kelch-like protein 3 *ENSDARG0000005664734
klhl2 / kelch-like family member 2 / O95198* / Q8JZP3* / Kelch-like protein 2 *ENSDARG0000006178634
klhl5 / kelch-like family member 5 / KLHL4* / KLHL1* / Q96PQ7* / Q9C0H6* / Q9NR64* / Q9JI74* / Kelch-like protein 1 * / kelch like family member 1* / kelch like family member 4* / kelch-lik...ENSDARG0000006212233
klhl10a / kelch-like family member 10a / Q9D5V2* / KLHL10* / Q6JEL2* / kelch-like 10* / kelch like family member 10*ENSDARG0000000581429
klhl10b.2 / kelch-like family member 10b, tandem duplicate 2 / Q9D5V2* / KLHL10* / Q6JEL2* / kelch-like 10* / kelch like family member 10*ENSDARG0000011217028
klhl10b.1 / kelch-like family member 10b, tandem duplicate 1 / Q9D5V2* / KLHL10* / Q6JEL2* / kelch-like 10* / kelch like family member 10*ENSDARG0000011548928
klhl8 / kelch-like family member 8 / Q9P2G9*ENSDARG0000010127028
KLHL28 / kelch like family member 28 / Q9NXS3*ENSDARG0000010167626
klhl12 / kelch-like family member 12 / Q53G59*ENSDARG0000010063118
KLHL12 (1 of many) / kelch like family member 12 / KLHL12* / Q53G59*ENSDARG0000011272817


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR006652  Kelch repeat type 1
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR011705  BTB/Kelch-associated
 IPR015915  Kelch-type beta propeller
 IPR017096  BTB-kelch protein
 IPR030563  Kelch-like ECH-associated protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0042994 cytoplasmic sequestering of transcription factor IBA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IBA
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity IBA
 biological_processGO:0071379 cellular response to prostaglandin stimulus IGI
 biological_processGO:0071466 cellular response to xenobiotic stimulus IGI
 cellular_componentGO:0031463 Cul3-RING ubiquitin ligase complex IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IBA
 molecular_functionGO:0008134 transcription factor binding IEA


Pathways (from Reactome)
Pathway description
Ub-specific processing proteases
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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