ENSDARG00000062122


Danio rerio

Features
Gene ID: ENSDARG00000062122
  
Biological name :klhl5
  
Synonyms : kelch-like family member 5 / klhl5
  
Possible biological names infered from orthology : kelch like family member 1 / kelch like family member 4 / Kelch-like protein 1 / kelch-like protein 4 isoform 3 / KLHL1 / KLHL4 / Mus musculus kelch-like 5 (Klhl5), transcript variant 2, mRNA. / Q96PQ7 / Q9C0H6 / Q9JI74 / Q9NR64
  
Species: Danio rerio
  
Chr. number: 1
Strand: -1
Band:
Gene start: 18363833
Gene end: 18446161
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000083875
NCBI entrez gene - 560697     See in Manteia.
RefSeq - NM_001170942
RefSeq Peptide - NP_001164413
swissprot - B8JIG8
ZFIN ID - ZDB-GENE-080424-7
Ensembl - ENSDARG00000062122
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KLHL1ENSGALG00000016907Gallus gallus
 KLHL4ENSGALG00000006877Gallus gallus
 KLHL5ENSGALG00000031388Gallus gallus
 KLHL1ENSG00000150361Homo sapiens
 KLHL4ENSG00000102271Homo sapiens
 KLHL5ENSG00000109790Homo sapiens
 Klhl1ENSMUSG00000022076Mus musculus
 Klhl4ENSMUSG00000025597Mus musculus
 Klhl5ENSMUSG00000054920Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
klhl20 / kelch-like family member 20 / Q8VCK5* / Q9Y2M5* / Kelch-like protein 20 *ENSDARG0000003880132
klhl17 / kelch-like family member 17 / Q6TDP3* / Q6TDP4* / Plekhn1* / Kelch-like protein 17 *ENSDARG0000003732432
klhl3 / kelch-like family member 3 / E0CZ16* / Q9UH77* / Kelch-like protein 3 *ENSDARG0000005664731
klhl2 / kelch-like family member 2 / O95198* / Q8JZP3* / Kelch-like protein 2 *ENSDARG0000006178630
klhl8 / kelch-like family member 8 / Q9P2G9*ENSDARG0000010127029
klhl18 / kelch-like family member 18 / O94889*ENSDARG0000000430629
KLHL28 / kelch like family member 28 / Q9NXS3*ENSDARG0000010167626
keap1b / kelch-like ECH-associated protein 1b / KEAP1* / Q9Z2X8* / Q14145* / kelch like ECH associated protein 1*ENSDARG0000007463425
keap1a / kelch-like ECH-associated protein 1aENSDARG0000001613224
klhl10a / kelch-like family member 10a / Q9D5V2* / KLHL10* / Q6JEL2* / kelch-like 10* / kelch like family member 10*ENSDARG0000000581424
klhl10b.2 / kelch-like family member 10b, tandem duplicate 2 / Q9D5V2* / KLHL10* / Q6JEL2* / kelch-like 10* / kelch like family member 10*ENSDARG0000011217023
klhl10b.1 / kelch-like family member 10b, tandem duplicate 1 / Q9D5V2* / KLHL10* / Q6JEL2* / kelch-like 10* / kelch like family member 10*ENSDARG0000011548923
klhl12 / kelch-like family member 12 / Q53G59*ENSDARG0000010063116
KLHL12 (1 of many) / kelch like family member 12 / KLHL12* / Q53G59*ENSDARG0000011272813


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR006652  Kelch repeat type 1
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR011705  BTB/Kelch-associated
 IPR015915  Kelch-type beta propeller


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 cellular_componentGO:0031463 Cul3-RING ubiquitin ligase complex IBA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IBA


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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