ENSG00000102271


Homo sapiens

Features
Gene ID: ENSG00000102271
  
Biological name :KLHL4
  
Synonyms : kelch like family member 4 / KLHL4 / Q9C0H6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: 1
Band: q21.31
Gene start: 87517749
Gene end: 87670050
  
Corresponding Affymetrix probe sets: 1553027_a_at (Human Genome U133 Plus 2.0 Array)   214591_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000362211
Ensembl peptide - ENSP00000362206
NCBI entrez gene - 56062     See in Manteia.
OMIM - 300348
RefSeq - NM_019117
RefSeq - NM_057162
RefSeq Peptide - NP_061990
RefSeq Peptide - NP_476503
swissprot - Q9C0H6
swissprot - A5PKX1
Ensembl - ENSG00000102271
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 klhl5ENSDARG00000062122Danio rerio
 KLHL4ENSGALG00000006877Gallus gallus
 Klhl4ENSMUSG00000025597Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KLHL1 / Q9NR64 / kelch like family member 1ENSG0000015036166
KLHL5 / Q96PQ7 / kelch like family member 5ENSG0000010979062
KLHL17 / Q6TDP4 / kelch like family member 17ENSG0000018796133
KLHL20 / Q9Y2M5 / kelch like family member 20ENSG0000007632133
KLHL2 / O95198 / kelch like family member 2ENSG0000010946631
KLHL28 / Q9NXS3 / kelch like family member 28ENSG0000017945431
KLHL3 / Q9UH77 / kelch like family member 3ENSG0000014602130
KLHL8 / Q9P2G9 / kelch like family member 8ENSG0000014533229
KLHL18 / O94889 / kelch like family member 18ENSG0000011464829
KLHL12 / Q53G59 / kelch like family member 12ENSG0000011715328
KEAP1 / Q14145 / kelch like ECH associated protein 1ENSG0000007999927
KLHL10 / Q6JEL2 / kelch like family member 10ENSG0000016159424


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR006652  Kelch repeat type 1
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR011705  BTB/Kelch-associated
 IPR015915  Kelch-type beta propeller


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 biological_processGO:0016567 protein ubiquitination IEA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005815 microtubule organizing center IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IDA
 cellular_componentGO:0031463 Cul3-RING ubiquitin ligase complex IBA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IBA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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