ENSG00000179454


Homo sapiens

Features
Gene ID: ENSG00000179454
  
Biological name :KLHL28
  
Synonyms : kelch like family member 28 / KLHL28 / Q9NXS3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q21.2
Gene start: 44924319
Gene end: 45042322
  
Corresponding Affymetrix probe sets: 220374_at (Human Genome U133 Plus 2.0 Array)   228328_at (Human Genome U133 Plus 2.0 Array)   235727_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000450788
Ensembl peptide - ENSP00000347193
Ensembl peptide - ENSP00000379434
Ensembl peptide - ENSP00000462025
Ensembl peptide - ENSP00000452061
Ensembl peptide - ENSP00000452591
NCBI entrez gene - 54813     See in Manteia.
RefSeq - XM_011536849
RefSeq - NM_001308112
RefSeq - NM_017658
RefSeq - XM_005267770
RefSeq - XM_011536847
RefSeq Peptide - NP_001295041
RefSeq Peptide - NP_060128
swissprot - G3V4Y0
swissprot - G3V5Y9
swissprot - J3KNY7
swissprot - Q9NXS3
swissprot - J3KRJ0
swissprot - G3V2P9
Ensembl - ENSG00000179454
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KLHL28ENSDARG00000101676Danio rerio
 KLHL28ENSGALG00000012489Gallus gallus
 Klhl28ENSMUSG00000020948Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KLHL20 / Q9Y2M5 / kelch like family member 20ENSG0000007632141
KLHL17 / Q6TDP4 / kelch like family member 17ENSG0000018796140
KLHL1 / Q9NR64 / kelch like family member 1ENSG0000015036139
KLHL4 / Q9C0H6 / kelch like family member 4ENSG0000010227138
KLHL5 / Q96PQ7 / kelch like family member 5ENSG0000010979038
KLHL12 / Q53G59 / kelch like family member 12ENSG0000011715337
KLHL2 / O95198 / kelch like family member 2ENSG0000010946637
KLHL3 / Q9UH77 / kelch like family member 3ENSG0000014602137
KLHL18 / O94889 / kelch like family member 18ENSG0000011464836
KEAP1 / Q14145 / kelch like ECH associated protein 1ENSG0000007999934
KLHL8 / Q9P2G9 / kelch like family member 8ENSG0000014533233
KLHL10 / Q6JEL2 / kelch like family member 10ENSG0000016159432


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR006652  Kelch repeat type 1
 IPR011043  Galactose oxidase/kelch, beta-propeller
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR011705  BTB/Kelch-associated
 IPR015915  Kelch-type beta propeller
 IPR017096  BTB-kelch protein
 IPR030569  Kelch-like protein 28


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 cellular_componentGO:0031463 Cul3-RING ubiquitin ligase complex IBA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IBA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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