ENSG00000109790


Homo sapiens

Features
Gene ID: ENSG00000109790
  
Biological name :KLHL5
  
Synonyms : kelch like family member 5 / KLHL5 / Q96PQ7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: p14
Gene start: 39045039
Gene end: 39126857
  
Corresponding Affymetrix probe sets: 226001_at (Human Genome U133 Plus 2.0 Array)   227565_at (Human Genome U133 Plus 2.0 Array)   232297_at (Human Genome U133 Plus 2.0 Array)   233866_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000426949
Ensembl peptide - ENSP00000423897
Ensembl peptide - ENSP00000425512
Ensembl peptide - ENSP00000261425
Ensembl peptide - ENSP00000261426
Ensembl peptide - ENSP00000371355
Ensembl peptide - ENSP00000423080
NCBI entrez gene - 51088     See in Manteia.
OMIM - 608064
RefSeq - XM_017008276
RefSeq - XM_005262655
RefSeq - XM_011513699
RefSeq - XM_011513700
RefSeq - XM_011513701
RefSeq - XM_017008273
RefSeq - XM_017008274
RefSeq - XM_017008275
RefSeq - NM_001007075
RefSeq - NM_001171654
RefSeq - NM_015990
RefSeq - NM_199039
RefSeq Peptide - NP_950240
RefSeq Peptide - NP_001007076
RefSeq Peptide - NP_001165125
RefSeq Peptide - NP_057074
swissprot - Q96PQ7
swissprot - H0YAF6
swissprot - H0Y9Y5
Ensembl - ENSG00000109790
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 klhl5ENSDARG00000062122Danio rerio
 KLHL5ENSGALG00000031388Gallus gallus
 Klhl5ENSMUSG00000054920Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KLHL1 / Q9NR64 / kelch like family member 1ENSG0000015036161
KLHL4 / Q9C0H6 / kelch like family member 4ENSG0000010227159
KLHL20 / Q9Y2M5 / kelch like family member 20ENSG0000007632133
KLHL17 / Q6TDP4 / kelch like family member 17ENSG0000018796133
KLHL2 / O95198 / kelch like family member 2ENSG0000010946631
KLHL3 / Q9UH77 / kelch like family member 3ENSG0000014602131
KLHL28 / Q9NXS3 / kelch like family member 28ENSG0000017945430
KLHL18 / O94889 / kelch like family member 18ENSG0000011464830
KLHL8 / Q9P2G9 / kelch like family member 8ENSG0000014533229
KLHL12 / Q53G59 / kelch like family member 12ENSG0000011715328
KEAP1 / Q14145 / kelch like ECH associated protein 1ENSG0000007999927
KLHL10 / Q6JEL2 / kelch like family member 10ENSG0000016159424


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR006652  Kelch repeat type 1
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR011705  BTB/Kelch-associated
 IPR015915  Kelch-type beta propeller
 IPR017096  BTB-kelch protein
 IPR037293  Galactose oxidase, central domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0043687 post-translational protein modification TAS
 cellular_componentGO:0005737 cytoplasm NAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0031463 Cul3-RING ubiquitin ligase complex IBA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IBA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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