ENSG00000150361


Homo sapiens

Features
Gene ID: ENSG00000150361
  
Biological name :KLHL1
  
Synonyms : kelch like family member 1 / KLHL1 / Q9NR64
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: -1
Band: q21.33
Gene start: 69700594
Gene end: 70108493
  
Corresponding Affymetrix probe sets: 216391_s_at (Human Genome U133 Plus 2.0 Array)   223810_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000367075
Ensembl peptide - ENSP00000439602
NCBI entrez gene - 57626     See in Manteia.
OMIM - 605332
RefSeq - XM_017020679
RefSeq - NM_001286725
RefSeq - NM_020866
RefSeq - XM_017020678
RefSeq Peptide - NP_065917
RefSeq Peptide - NP_001273654
swissprot - Q9NR64
swissprot - F5H1J3
Ensembl - ENSG00000150361
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 klhl5ENSDARG00000062122Danio rerio
 KLHL1ENSGALG00000016907Gallus gallus
 Klhl1ENSMUSG00000022076Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KLHL4 / Q9C0H6 / kelch like family member 4ENSG0000010227164
KLHL5 / Q96PQ7 / kelch like family member 5ENSG0000010979062
KLHL20 / Q9Y2M5 / kelch like family member 20ENSG0000007632134
KLHL17 / Q6TDP4 / kelch like family member 17ENSG0000018796132
KLHL28 / Q9NXS3 / kelch like family member 28ENSG0000017945431
KLHL3 / Q9UH77 / kelch like family member 3ENSG0000014602130
KLHL18 / O94889 / kelch like family member 18ENSG0000011464830
KLHL2 / O95198 / kelch like family member 2ENSG0000010946630
KLHL8 / Q9P2G9 / kelch like family member 8ENSG0000014533230
KLHL12 / Q53G59 / kelch like family member 12ENSG0000011715329
KEAP1 / Q14145 / kelch like ECH associated protein 1ENSG0000007999928
KLHL10 / Q6JEL2 / kelch like family member 10ENSG0000016159425


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR006652  Kelch repeat type 1
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR011705  BTB/Kelch-associated
 IPR015915  Kelch-type beta propeller
 IPR017096  BTB-kelch protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007626 locomotory behavior IEA
 biological_processGO:0007628 adult walking behavior IEA
 biological_processGO:0016358 dendrite development IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0021680 cerebellar Purkinje cell layer development IEA
 biological_processGO:0030036 actin cytoskeleton organization NAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0031463 Cul3-RING ubiquitin ligase complex IBA
 cellular_componentGO:0043025 neuronal cell body IEA
 molecular_functionGO:0003779 actin binding NAS
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IBA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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