ENSG00000187961


Homo sapiens

Features
Gene ID: ENSG00000187961
  
Biological name :KLHL17
  
Synonyms : kelch like family member 17 / KLHL17 / Q6TDP4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p36.33
Gene start: 960587
Gene end: 965715
  
Corresponding Affymetrix probe sets: 1555650_at (Human Genome U133 Plus 2.0 Array)   229792_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000343930
Ensembl peptide - ENSP00000463694
Ensembl peptide - ENSP00000479477
NCBI entrez gene - 339451     See in Manteia.
RefSeq - XM_006710600
RefSeq - NM_198317
RefSeq Peptide - NP_938073
swissprot - Q0VGE6
swissprot - Q6TDP4
swissprot - J3QLT4
Ensembl - ENSG00000187961
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 klhl17ENSDARG00000037324Danio rerio
 KLHL17ENSGALG00000002199Gallus gallus
 Q6TDP3ENSMUSG00000078485Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KLHL20 / Q9Y2M5 / kelch like family member 20ENSG0000007632144
KLHL2 / O95198 / kelch like family member 2ENSG0000010946643
KLHL3 / Q9UH77 / kelch like family member 3ENSG0000014602143
KLHL5 / Q96PQ7 / kelch like family member 5ENSG0000010979039
KLHL18 / O94889 / kelch like family member 18ENSG0000011464838
KLHL4 / Q9C0H6 / kelch like family member 4ENSG0000010227137
KLHL1 / Q9NR64 / kelch like family member 1ENSG0000015036137
KLHL28 / Q9NXS3 / kelch like family member 28ENSG0000017945436
KLHL12 / Q53G59 / kelch like family member 12ENSG0000011715336
KEAP1 / Q14145 / kelch like ECH associated protein 1ENSG0000007999935
KLHL8 / Q9P2G9 / kelch like family member 8ENSG0000014533233
KLHL10 / Q6JEL2 / kelch like family member 10ENSG0000016159430


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR006652  Kelch repeat type 1
 IPR011043  Galactose oxidase/kelch, beta-propeller
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR011705  BTB/Kelch-associated
 IPR015915  Kelch-type beta propeller
 IPR017096  BTB-kelch protein
 IPR030594  Kelch-like protein 17
 IPR037293  Galactose oxidase, central domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007420 brain development IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0030036 actin cytoskeleton organization IEA
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0031463 Cul3-RING ubiquitin ligase complex IBA
 cellular_componentGO:0032839 dendrite cytoplasm IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0031208 POZ domain binding IEA
 molecular_functionGO:0032947 protein-containing complex scaffold activity IEA
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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