ENSMUSG00000078485


Mus musculus

Features
Gene ID: ENSMUSG00000078485
  
Biological name :Plekhn1
  
Synonyms : Kelch-like protein 17 / Plekhn1 / Q6TDP3
  
Possible biological names infered from orthology : kelch like family member 17 / KLHL17 / Q6TDP4
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: E2
Gene start: 156221456
Gene end: 156234857
  
Corresponding Affymetrix probe sets: 10608717 (MoGene1.0st)   10608719 (MoGene1.0st)   1435257_at (Mouse Genome 430 2.0 Array)   1452329_at (Mouse Genome 430 2.0 Array)   1456253_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000101196
Ensembl peptide - ENSMUSP00000101194
Ensembl peptide - ENSMUSP00000151799
Ensembl peptide - ENSMUSP00000151311
NCBI entrez gene - 231002     See in Manteia.
NCBI entrez gene - 231003     See in Manteia.
MGI - MGI:2387630
RefSeq - NM_001008233
RefSeq - NM_198305
RefSeq Peptide - NP_001008234
RefSeq Peptide - NP_938047
swissprot - Q6TDP3
swissprot - B2RTE7
swissprot - A0A1W2P7X5
swissprot - A0A1W2P6Q7
swissprot - E9QP36
Ensembl - ENSMUSG00000078485
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 klhl17ENSDARG00000037324Danio rerio
 KLHL17ENSGALG00000002199Gallus gallus
 KLHL17ENSG00000187961Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Klhl2 / Q8JZP3 / Kelch-like protein 2 / O95198* / kelch like family member 2*ENSMUSG0000003160544
Klhl20 / Q8VCK5 / Kelch-like protein 20 / Q9Y2M5* / kelch like family member 20*ENSMUSG0000002670544
Klhl3 / E0CZ16 / Kelch-like protein 3 / Q9UH77* / kelch like family member 3*ENSMUSG0000001416443
Klhl5 / Mus musculus kelch-like 5 (Klhl5), transcript variant 2, mRNA. / Q96PQ7* / kelch like family member 5*ENSMUSG0000005492039
Klhl18 / kelch like family member 18 / O94889*ENSMUSG0000005479238
Klhl4 / kelch-like protein 4 isoform 3 / Q9C0H6* / kelch like family member 4*ENSMUSG0000002559738
Klhl1 / Q9JI74 / Kelch-like protein 1 / Q9NR64* / kelch like family member 1*ENSMUSG0000002207637
Klhl12 / Q8BZM0 / Kelch-like protein 12 / Q53G59* / kelch like family member 12*ENSMUSG0000002645536
Klhl28 / Q9CR40 / Kelch-like protein 28 / Q9NXS3* / kelch like family member 28*ENSMUSG0000002094836
Keap1 / Q9Z2X8 / Kelch-like ECH-associated protein 1 / Q14145*ENSMUSG0000000330834
Klhl8 / P59280 / Kelch-like protein 8 / Q9P2G9* / kelch like family member 8*ENSMUSG0000002931233
Klhl10 / Q9D5V2 / kelch-like 10 / Q6JEL2* / kelch like family member 10*ENSMUSG0000000155831


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR001849  Pleckstrin homology domain
 IPR006652  Kelch repeat type 1
 IPR011043  Galactose oxidase/kelch, beta-propeller
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR011705  BTB/Kelch-associated
 IPR011993  PH-like domain superfamily
 IPR015915  Kelch-type beta propeller
 IPR017096  BTB-kelch protein
 IPR030594  Kelch-like protein 17
 IPR037293  Galactose oxidase, central domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007420 brain development IBA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0030036 actin cytoskeleton organization IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0015629 actin cytoskeleton IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0031463 Cul3-RING ubiquitin ligase complex IBA
 cellular_componentGO:0032839 dendrite cytoplasm IBA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0031208 POZ domain binding IEA
 molecular_functionGO:0032947 protein-containing complex scaffold activity IEA
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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