ENSMUSG00000031605


Mus musculus

Features
Gene ID: ENSMUSG00000031605
  
Biological name :Klhl2
  
Synonyms : Kelch-like protein 2 / Klhl2 / Q8JZP3
  
Possible biological names infered from orthology : kelch like family member 2 / O95198
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: B3.1
Gene start: 64739675
Gene end: 64850017
  
Corresponding Affymetrix probe sets: 10578922 (MoGene1.0st)   1426978_at (Mouse Genome 430 2.0 Array)   1458351_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000034017
Ensembl peptide - ENSMUSP00000147262
NCBI entrez gene - 77113     See in Manteia.
MGI - MGI:1924363
RefSeq - XM_017313012
RefSeq - NM_178633
RefSeq - XM_017313011
RefSeq Peptide - NP_848748
swissprot - Q8JZP3
swissprot - A0A1B0GQV2
Ensembl - ENSMUSG00000031605
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 klhl2ENSDARG00000061786Danio rerio
 KLHL2ENSGALG00000009554Gallus gallus
 KLHL2ENSG00000109466Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Klhl3 / E0CZ16 / Kelch-like protein 3 / Q9UH77* / kelch like family member 3*ENSMUSG0000001416475
Q6TDP3 / Plekhn1 / Kelch-like protein 17 / KLHL17* / Q6TDP4* / kelch like family member 17*ENSMUSG0000007848547
Klhl20 / Q8VCK5 / Kelch-like protein 20 / Q9Y2M5* / kelch like family member 20*ENSMUSG0000002670542
Klhl5 / Mus musculus kelch-like 5 (Klhl5), transcript variant 2, mRNA. / Q96PQ7* / kelch like family member 5*ENSMUSG0000005492040
Klhl12 / Q8BZM0 / Kelch-like protein 12 / Q53G59* / kelch like family member 12*ENSMUSG0000002645540
Klhl1 / Q9JI74 / Kelch-like protein 1 / Q9NR64* / kelch like family member 1*ENSMUSG0000002207638
Klhl4 / kelch-like protein 4 isoform 3 / Q9C0H6* / kelch like family member 4*ENSMUSG0000002559738
Klhl18 / kelch like family member 18 / O94889*ENSMUSG0000005479237
Klhl8 / P59280 / Kelch-like protein 8 / Q9P2G9* / kelch like family member 8*ENSMUSG0000002931236
Klhl28 / Q9CR40 / Kelch-like protein 28 / Q9NXS3* / kelch like family member 28*ENSMUSG0000002094836
Keap1 / Q9Z2X8 / Kelch-like ECH-associated protein 1 / Q14145*ENSMUSG0000000330836
Klhl10 / Q9D5V2 / kelch-like 10 / Q6JEL2* / kelch like family member 10*ENSMUSG0000000155834


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR006652  Kelch repeat type 1
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR011705  BTB/Kelch-associated
 IPR015915  Kelch-type beta propeller
 IPR017096  BTB-kelch protein
 IPR037293  Galactose oxidase, central domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IDA
 cellular_componentGO:0001725 stress fiber ISO
 cellular_componentGO:0001726 ruffle IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0031463 Cul3-RING ubiquitin ligase complex IDA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0003779 actin binding IBA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity ISO


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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