ENSG00000114648


Homo sapiens

Features
Gene ID: ENSG00000114648
  
Biological name :KLHL18
  
Synonyms : kelch like family member 18 / KLHL18 / O94889
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p21.31
Gene start: 47282917
Gene end: 47346816
  
Corresponding Affymetrix probe sets: 1557165_s_at (Human Genome U133 Plus 2.0 Array)   207976_at (Human Genome U133 Plus 2.0 Array)   212882_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000407114
Ensembl peptide - ENSP00000411839
Ensembl peptide - ENSP00000232766
Ensembl peptide - ENSP00000392507
NCBI entrez gene - 23276     See in Manteia.
RefSeq - XM_017006035
RefSeq - XM_005265001
RefSeq - XM_005265002
RefSeq - XM_005265003
RefSeq - XM_006713079
RefSeq - XM_017006033
RefSeq - XM_017006034
RefSeq - NM_025010
RefSeq Peptide - NP_079286
swissprot - C9J4G4
swissprot - F8WCL4
swissprot - F8WF78
swissprot - A0A024R2T4
swissprot - O94889
Ensembl - ENSG00000114648
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 klhl18ENSDARG00000004306Danio rerio
 KLHL18ENSGALG00000005582Gallus gallus
 Klhl18ENSMUSG00000054792Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KLHL17 / Q6TDP4 / kelch like family member 17ENSG0000018796142
KLHL20 / Q9Y2M5 / kelch like family member 20ENSG0000007632140
KLHL12 / Q53G59 / kelch like family member 12ENSG0000011715339
KLHL5 / Q96PQ7 / kelch like family member 5ENSG0000010979039
KLHL1 / Q9NR64 / kelch like family member 1ENSG0000015036139
KLHL2 / O95198 / kelch like family member 2ENSG0000010946638
KLHL3 / Q9UH77 / kelch like family member 3ENSG0000014602137
KLHL28 / Q9NXS3 / kelch like family member 28ENSG0000017945437
KLHL4 / Q9C0H6 / kelch like family member 4ENSG0000010227136
KLHL8 / Q9P2G9 / kelch like family member 8ENSG0000014533235
KEAP1 / Q14145 / kelch like ECH associated protein 1ENSG0000007999935
KLHL10 / Q6JEL2 / kelch like family member 10ENSG0000016159430


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR006652  Kelch repeat type 1
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR011705  BTB/Kelch-associated
 IPR015915  Kelch-type beta propeller
 IPR017096  BTB-kelch protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 cellular_componentGO:0031463 Cul3-RING ubiquitin ligase complex IBA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IBA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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