ENSDARG00000074667


Danio rerio

Features
Gene ID: ENSDARG00000074667
  
Biological name :akt1s1
  
Synonyms : akt1s1 / AKT1 substrate 1 (proline-rich)
  
Possible biological names infered from orthology : AKT1 substrate 1 / Proline-rich AKT1 substrate 1 / Q96B36 / Q9D1F4
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 30190419
Gene end: 30200557
  
Corresponding Affymetrix probe sets: Dr.12134.2.A1_at (Zebrafish Array)   XM_687419_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000128295
NCBI entrez gene - 566559     See in Manteia.
RefSeq - XM_687419
swissprot - E7EY34
ZFIN ID - ZDB-GENE-030131-482
Ensembl - ENSDARG00000074667
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AKT1S1ENSG00000204673Homo sapiens
 Akt1s1ENSMUSG00000011096Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026682  Proline-rich AKT1 substrate 1 protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006469 negative regulation of protein kinase activity IBA
 biological_processGO:0032007 negative regulation of TOR signaling IBA
 biological_processGO:0038202 TORC1 signaling IBA
 biological_processGO:0048011 neurotrophin TRK receptor signaling pathway IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0031931 TORC1 complex IBA


Pathways (from Reactome)
Pathway description
mTOR signalling
mTORC1-mediated signalling
AKT phosphorylates targets in the cytosol
HSF1-dependent transactivation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000003167 mlst8 / Q803V5 / MTOR associated protein, LST8 homolog (S. cerevisiae) / Q9BVC4* / Q9DCJ1* / MTOR associated protein, LST8 homolog* / Target of rapamycin complex subunit LST8 *  / complex / reaction
 ENSDARG00000032769 Q08BA4 / slc38a9 / solute carrier family 38, member 9 / Q8NBW4*  / complex / reaction
 ENSDARG00000098726 rptor / regulatory associated protein of MTOR, complex 1 / Q8N122*  / complex / reaction
 ENSDARG00000013078 ywhaba / Q5PRD0 / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a / YWHAB* / P31946* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activat...  / complex / reaction
 ENSDARG00000074667 akt1s1 / AKT1 substrate 1 (proline-rich) / Q96B36* / Q9D1F4* / AKT1 substrate 1* / Proline-rich AKT1 substrate 1 *  / complex






 

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