ENSDARG00000074675


Danio rerio

Features
Gene ID: ENSDARG00000074675
  
Biological name :pan2
  
Synonyms : pan2 / PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
  
Possible biological names infered from orthology : PAN2-PAN3 deadenylation complex catalytic subunit Pan2 / PAN2 poly(A) specific ribonuclease subunit / Q504Q3 / Q8BGF7
  
Species: Danio rerio
  
Chr. number: 23
Strand: 1
Band:
Gene start: 31979602
Gene end: 32007818
  
Corresponding Affymetrix probe sets: Dr.2690.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000151470
Ensembl peptide - ENSDARP00000118293
NCBI entrez gene - 792831     See in Manteia.
RefSeq - XM_001919965
RefSeq - XM_005162345
swissprot - E9QJN4
ZFIN ID - ZDB-GENE-030131-3113
Ensembl - ENSDARG00000074675
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PAN2ENSGALG00000031512Gallus gallus
 PAN2ENSG00000135473Homo sapiens
 Pan2ENSMUSG00000005682Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR012337  Ribonuclease H-like superfamily
 IPR013520  Exonuclease, RNase T/DNA polymerase III
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR028881  PAN2 domain
 IPR028889  Ubiquitin specific protease domain
 IPR030843  PAN2-PAN3 deadenylation complex catalytic subunit PAN2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay IEA
 biological_processGO:0000289 nuclear-transcribed mRNA poly(A) tail shortening IEA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0010606 positive regulation of cytoplasmic mRNA processing body assembly IEA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 biological_processGO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic IEA
 cellular_componentGO:0000932 P-body IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0031251 PAN complex IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004527 exonuclease activity IEA
 molecular_functionGO:0004535 poly(A)-specific ribonuclease activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Deadenylation of mRNA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000031637 pan3 / PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae) / Q58A45* / Q640Q5* / PAN3 poly(A) specific ribonuclease subunit* / PAN2-PAN3 deadenylation complex subunit Pan3 *  / complex






 

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