ENSDARG00000075952


Danio rerio

Features
Gene ID: ENSDARG00000075952
  
Biological name :mbd2
  
Synonyms : mbd2 / methyl-CpG binding domain protein 2
  
Possible biological names infered from orthology : Q9UBB5 / Q9Z2E1
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 998296
Gene end: 1047504
  
Corresponding Affymetrix probe sets: Dr.23525.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000136077
Ensembl peptide - ENSDARP00000154272
swissprot - A0A0R4INE2
swissprot - E7F3L2
ZFIN ID - ZDB-GENE-030131-9049
Ensembl - ENSDARG00000075952
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MBD2ENSG00000134046Homo sapiens
 Mbd2ENSMUSG00000024513Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mbd3a / methyl-CpG binding domain protein 3a / MBD3* / MBD3L1* / MBD3L2* / MBD3L3* / MBD3L4* / MBD3L5* / Q9Z2D8* / O95983* / A6NDZ8* / A6NE82* / A6NJ08* / Q8NHZ7* / Q9D9H3* / Q8WWY6* / MBD3...ENSDARG0000006177457


Protein motifs (from Interpro)
Interpro ID Name
 IPR001739  Methyl-CpG DNA binding
 IPR016177  DNA-binding domain superfamily
 IPR032343  Methyl-CpG-binding domain protein 2/3, p55-binding region


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IBA
 biological_processGO:0006346 methylation-dependent chromatin silencing IBA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0008327 methyl-CpG binding IBA


Pathways (from Reactome)
Pathway description
NoRC negatively regulates rRNA expression
RNA Polymerase I Promoter Opening


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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