ENSDARG00000061774


Danio rerio

Features
Gene ID: ENSDARG00000061774
  
Biological name :mbd3a
  
Synonyms : mbd3a / methyl-CpG binding domain protein 3a
  
Possible biological names infered from orthology : A0A1B0GVZ6 / A6NDZ8 / A6NE82 / A6NJ08 / MBD3 / MBD3L1 / MBD3L2 / MBD3L2B / MBD3L3 / MBD3L4 / MBD3L5 / methyl-CpG binding domain protein 3 / methyl-CpG binding domain protein 3 like 1 / methyl-CpG binding domain protein 3 like 2 / methyl-CpG binding domain protein 3 like 2B / methyl-CpG binding domain protein 3 like 3 / methyl-CpG binding domain protein 3 like 4 / methyl-CpG binding domain protein 3 like 5 / O95983 / Q8NHZ7 / Q8WWY6 / Q9D9H3 / Q9Z2D8
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 57239978
Gene end: 57264334
  
Corresponding Affymetrix probe sets: Dr.15443.1.S1_at (Zebrafish Array)   NM_212769_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000082941
Ensembl peptide - ENSDARP00000123868
Ensembl peptide - ENSDARP00000124340
Ensembl peptide - ENSDARP00000154556
NCBI entrez gene - 337133     See in Manteia.
RefSeq - NM_212769
RefSeq - XM_005168451
RefSeq Peptide - NP_997934
swissprot - Q6TGX7
swissprot - Q7ZTV2
ZFIN ID - ZDB-GENE-030131-9077
Ensembl - ENSDARG00000061774
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MBD3ENSGALG00000001101Gallus gallus
 A6NDZ8ENSG00000205718Homo sapiens
 A6NE82ENSG00000182315Homo sapiens
 A6NJ08ENSG00000237247Homo sapiens
 MBD3ENSG00000071655Homo sapiens
 MBD3L1ENSG00000170948Homo sapiens
 MBD3L2ENSG00000230522Homo sapiens
 MBD3L2BENSG00000196589Homo sapiens
 Mbd3ENSMUSG00000035478Mus musculus
 Mbd3l1ENSMUSG00000038691Mus musculus
 Mbd3l2ENSMUSG00000047508Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mbd2 / methyl-CpG binding domain protein 2 / Q9UBB5* / Q9Z2E1*ENSDARG0000007595240


Protein motifs (from Interpro)
Interpro ID Name
 IPR001739  Methyl-CpG DNA binding
 IPR016177  DNA-binding domain superfamily
 IPR025884  Methyl-CpG binding protein 2/3, C-terminal domain
 IPR032343  Methyl-CpG-binding domain protein 2/3, p55-binding region


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IBA
 biological_processGO:0006346 methylation-dependent chromatin silencing IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0016581 NuRD complex IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0008327 methyl-CpG binding IBA


Pathways (from Reactome)
Pathway description
Regulation of TP53 Activity through Acetylation
RNA Polymerase I Transcription Initiation
Regulation of PTEN gene transcription


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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