ENSG00000205718


Homo sapiens

Features
Gene ID: ENSG00000205718
  
Biological name :MBD3L4
  
Synonyms : A6NDZ8 / MBD3L4 / methyl-CpG binding domain protein 3 like 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.2
Gene start: 7037748
Gene end: 7040179
  
Corresponding Affymetrix probe sets: 1552456_a_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000370801
NCBI entrez gene - 653656     See in Manteia.
RefSeq - NM_001164419
RefSeq Peptide - NP_001157891
swissprot - A6NDZ8
Ensembl - ENSG00000205718
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mbd3aENSDARG00000061774Danio rerio
 MBD3ENSGALG00000001101Gallus gallus
 Mbd3l2ENSMUSG00000047508Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A6NE82 / MBD3L3 / methyl-CpG binding domain protein 3 like 3ENSG00000182315100
A6NJ08 / MBD3L5 / methyl-CpG binding domain protein 3 like 5ENSG0000023724799
MBD3L2 / Q8NHZ7 / methyl-CpG binding domain protein 3 like 2ENSG0000023052297
MBD3L2B / A0A1B0GVZ6 / methyl-CpG binding domain protein 3 like 2BENSG0000019658997
MBD3L1 / Q8WWY6 / methyl-CpG binding domain protein 3 like 1ENSG0000017094835
MBD3 / O95983 / methyl-CpG binding domain protein 3ENSG0000007165529
MBD2 / Q9UBB5 / methyl-CpG binding domain protein 2ENSG0000013404628


Protein motifs (from Interpro)
Interpro ID Name
 IPR025884  Methyl-CpG binding protein 2/3, C-terminal domain
 IPR032343  Methyl-CpG-binding domain protein 2/3, p55-binding region


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IBA
 biological_processGO:0006346 methylation-dependent chromatin silencing IBA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0008327 methyl-CpG binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr