ENSDARG00000076001


Danio rerio

Features
Gene ID: ENSDARG00000076001
  
Biological name :pip5k1ca
  
Synonyms : phosphatidylinositol-4-phosphate 5-kinase, type I, gamma a / pip5k1ca
  
Possible biological names infered from orthology : O60331 / O70161 / phosphatidylinositol-4-phosphate 5-kinase type 1 gamma / PIP5K1C
  
Species: Danio rerio
  
Chr. number: 22
Strand: -1
Band:
Gene start: 17543607
Gene end: 17586112
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000155945
Ensembl peptide - ENSDARP00000156249
Ensembl peptide - ENSDARP00000060785
Ensembl peptide - ENSDARP00000146209
Ensembl peptide - ENSDARP00000147543
Ensembl peptide - ENSDARP00000153685
NCBI entrez gene - 798876     See in Manteia.
swissprot - E7F4U5
ZFIN ID - ZDB-GENE-050208-358
Ensembl - ENSDARG00000076001
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PIP5K1CENSGALG00000000784Gallus gallus
 O60331ENSG00000186111Homo sapiens
 O70161ENSMUSG00000034902Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pip5k1cb / phosphatidylinositol-4-phosphate 5-kinase, type I, gamma b / O60331* / O70161* / PIP5K1C* / phosphatidylinositol-4-phosphate 5-kinase type 1 gamma*ENSDARG0000010031371
pip5k1ab / phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, b / P70182* / Q99755* / PIP5K1A* / phosphatidylinositol-4-phosphate 5-kinase type 1 alpha*ENSDARG0000002464250
pip5k1bb / phosphatidylinositol-4-phosphate 5-kinase, type I, beta b / O14986* / P70181* / PIP5K1B* / phosphatidylinositol-4-phosphate 5-kinase type 1 beta*ENSDARG0000000650850
pip5k1aa / phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, a / P70182* / Q99755* / PIP5K1A* / phosphatidylinositol-4-phosphate 5-kinase type 1 alpha*ENSDARG0000010039648
pip5k1ba / phosphatidylinositol-4-phosphate 5-kinase, type I, beta a / O14986* / P70181* / PIP5K1B* / phosphatidylinositol-4-phosphate 5-kinase type 1 beta*ENSDARG0000004429545
pip4k2aa / phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a / O70172* / P48426* / PIP4K2A* / phosphatidylinositol-5-phosphate 4-kinase type 2 alpha*ENSDARG0000000377618
pip4k2cb / phosphatidylinositol-5-phosphate 4-kinase, type II, gamma b / Q8TBX8* / PIP4K2C* / phosphatidylinositol-5-phosphate 4-kinase type 2 gamma*ENSDARG0000009163718
pip4k2ab / phosphatidylinositol-5-phosphate 4-kinase, type II, alpha b / O70172* / P48426* / PIP4K2A* / phosphatidylinositol-5-phosphate 4-kinase type 2 alpha*ENSDARG0000006354417
pip4k2ca / phosphatidylinositol-5-phosphate 4-kinase, type II, gamma a / Q8TBX8* / PIP4K2C* / phosphatidylinositol-5-phosphate 4-kinase type 2 gamma*ENSDARG0000003102017
pip5kl1 / phosphatidylinositol-4-phosphate 5-kinase-like 1 / Q5T9C9* / Q6U7H8* / Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 *ENSDARG0000006094615
si:dkey-3h23.3 / O14986* / P70181* / PIP5K1B* / phosphatidylinositol-4-phosphate 5-kinase type 1 beta*ENSDARG0000010484914


Protein motifs (from Interpro)
Interpro ID Name
 IPR002498  Phosphatidylinositol-4-phosphate 5-kinase, core
 IPR023610  Phosphatidylinositol-4-phosphate 5-kinase
 IPR027483  Phosphatidylinositol-4-phosphate 5-kinase, C-terminal
 IPR027484  Phosphatidylinositol-4-phosphate 5-kinase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0046488 phosphatidylinositol metabolic process IEA
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016307 phosphatidylinositol phosphate kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of PIPs at the plasma membrane
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000016429 farp2 / FERM, RhoGEF and pleckstrin domain protein 2 / O94887* / Q91VS8* / FERM, ARH/RhoGEF and pleckstrin domain protein 2* / FERM, ARHGEF and pleckstrin domain-containing protein 2 *  / reaction / complex
 ENSDARG00000100729 tln1 / talin 1 / P26039* / Q9Y490*  / complex






 

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