ENSDARG00000076718


Danio rerio

Features
Gene ID: ENSDARG00000076718
  
Biological name :prkra
  
Synonyms : B0V3F8 / prkra / protein kinase, interferon-inducible double stranded RNA dependent activator
  
Possible biological names infered from orthology : Interferon-inducible double-stranded RNA-dependent protein kinase activator A / O75569 / protein activator of interferon induced protein kinase EIF2AK2 / Q9WTX2
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 1365747
Gene end: 1371519
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000036697
Ensembl peptide - ENSDARP00000115290
NCBI entrez gene - 557370     See in Manteia.
RefSeq - NM_001089361
RefSeq - XM_005172508
RefSeq Peptide - NP_001082830
swissprot - F1Q8C8
swissprot - B0V3F8
swissprot - B0V3F9
ZFIN ID - ZDB-GENE-050309-206
Ensembl - ENSDARG00000076718
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PRKRAENSG00000180228Homo sapiens
 PrkraENSMUSG00000002731Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tarbp2 / TAR (HIV) RNA binding protein 2 / P97473* / Q15633* / TARBP2, RISC loading complex RNA binding subunit*ENSDARG0000007047146


Protein motifs (from Interpro)
Interpro ID Name
 IPR007110  Immunoglobulin-like domain
 IPR014720  Double-stranded RNA-binding domain
 IPR032478  Staufen, C-terminal
 IPR033363  Interferon-inducible double-stranded RNA-dependent protein kinase activator A


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0030422 production of siRNA involved in RNA interference ISS
 biological_processGO:0031047 gene silencing by RNA IEA
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003725 double-stranded RNA binding IEA
 molecular_functionGO:0008047 enzyme activator activity IEA
 molecular_functionGO:0016301 kinase activity IEA


Pathways (from Reactome)
Pathway description
MicroRNA (miRNA) biogenesis
Small interfering RNA (siRNA) biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000001129 dicer1 / Q6TV19 / dicer 1, ribonuclease type III / Q9UPY3* / dicer 1, ribonuclease III*  / complex






 

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