ENSDARG00000076853


Danio rerio

Features
Gene ID: ENSDARG00000076853
  
Biological name :areg
  
Synonyms : amphiregulin / areg
  
Possible biological names infered from orthology : Mcub / P15514 / P31955
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 6755466
Gene end: 6790840
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000101371
Ensembl peptide - ENSDARP00000136140
NCBI entrez gene - 101884611     See in Manteia.
swissprot - A0A0R4IJX2
swissprot - F1RB57
ZFIN ID - ZDB-GENE-141216-239
Ensembl - ENSDARG00000076853
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AREGENSGALG00000010866Gallus gallus
 AREGENSG00000109321Homo sapiens
 McubENSMUSG00000029378Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
hbegfb / heparin-binding EGF-like growth factor b / HBEGF* / Q06186* / Q99075* / heparin binding EGF like growth factor* / Proheparin-binding EGF-like growth factor Heparin-binding EGF-like...ENSDARG0000003124621
hbegfa / heparin-binding EGF-like growth factor a / HBEGF* / Q06186* / Q99075* / heparin binding EGF like growth factor* / Proheparin-binding EGF-like growth factor Heparin-binding EGF-like...ENSDARG0000007512120


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR013032  EGF-like, conserved site
 IPR015497  Epidermal growth factor receptor ligand


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007173 epidermal growth factor receptor signaling pathway IBA
 biological_processGO:0008284 positive regulation of cell proliferation IBA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005154 epidermal growth factor receptor binding IBA
 molecular_functionGO:0008083 growth factor activity IBA


Pathways (from Reactome)
Pathway description
COPII-mediated vesicle transport
Cargo concentration in the ER


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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