ENSDARG00000076913


Danio rerio

Features
Gene ID: ENSDARG00000076913
  
Biological name :eme1
  
Synonyms : eme1 / essential meiotic structure-specific endonuclease 1
  
Possible biological names infered from orthology : Crossover junction endonuclease EME1 / Q8BJW7 / Q96AY2
  
Species: Danio rerio
  
Chr. number: 12
Strand: -1
Band:
Gene start: 21669385
Gene end: 21684255
  
Corresponding Affymetrix probe sets: Dr.21926.1.A1_at (Zebrafish Array)   Dr.4460.1.A1_at (Zebrafish Array)   Dr.4460.2.S1_at (Zebrafish Array)   Dr.4460.3.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000127438
Ensembl peptide - ENSDARP00000127450
Ensembl peptide - ENSDARP00000097532
Ensembl peptide - ENSDARP00000123940
Ensembl peptide - ENSDARP00000127132
NCBI entrez gene - 558350     See in Manteia.
swissprot - E7F6N8
swissprot - U3JA67
swissprot - U3JB16
swissprot - U3JB28
ZFIN ID - ZDB-GENE-030131-3191
Ensembl - ENSDARG00000076913
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EME1ENSGALG00000007676Gallus gallus
 EME1ENSG00000154920Homo sapiens
 Eme1ENSMUSG00000039055Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006166  ERCC4 domain
 IPR033310  Mms4/EME1/EME2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000712 resolution of meiotic recombination intermediates IBA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006302 double-strand break repair IBA
 biological_processGO:0031297 replication fork processing IBA
 biological_processGO:0031573 intra-S DNA damage checkpoint IBA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 cellular_componentGO:0000790 nuclear chromatin IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0048476 Holliday junction resolvase complex IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0008821 crossover junction endodeoxyribonuclease activity IBA


Pathways (from Reactome)
Pathway description
Resolution of D-loop Structures through Holliday Junction Intermediates
Fanconi Anemia Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000061414 slx4 / SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae) / Q8IY92* / Q6P1D7* / SLX4 structure-specific endonuclease subunit* / Structure-specific endonuclease subunit SLX4 *  / reaction / complex
 ENSDARG00000069326 mus81 / MUS81 structure-specific endonuclease subunit / Q91ZJ0* / Q96NY9* / Crossover junction endonuclease MUS81 *  / reaction / complex
 ENSDARG00000098605 slx1b / SLX1 homolog B, structure-specific endonuclease subunit / SLX1A* / Q9BQ83* / Q8BX32* / SLX1 homolog A, structure-specific endonuclease subunit* / SLX1 structure-specific endonucleas...  / complex / reaction






 

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