ENSDARG00000077029


Danio rerio

Features
Gene ID: ENSDARG00000077029
  
Biological name :bub1
  
Synonyms : bub1 / BUB1 mitotic checkpoint serine/threonine kinase
  
Possible biological names infered from orthology : mitotic checkpoint serine/threonine-protein kinase BUB1 isoform 2 / O43683
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 2610550
Gene end: 2641246
  
Corresponding Affymetrix probe sets: Dr.11972.1.A1_at (Zebrafish Array)   Dr.17403.1.A1_at (Zebrafish Array)   Dr.17403.1.A1_s_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000119299
Ensembl peptide - ENSDARP00000117438
Ensembl peptide - ENSDARP00000155440
NCBI entrez gene - 100307076     See in Manteia.
swissprot - B0VJZ8
swissprot - F1QNS6
ZFIN ID - ZDB-GENE-081104-75
Ensembl - ENSDARG00000077029
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BUB1ENSGALG00000008233Gallus gallus
 BUB1ENSG00000169679Homo sapiens
 Bub1ENSMUSG00000027379Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
bub1ba / BUB1 mitotic checkpoint serine/threonine kinase BaENSDARG0000007882510
bub1bb / BUB1 mitotic checkpoint serine/threonine kinase Bb / BUB1B* / O60566* / BUB1 mitotic checkpoint serine/threonine kinase B*ENSDARG000000749276


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013212  Mad3/Bub1 homology region 1
 IPR015661  Mitotic spindle checkpoint protein Bub1/Mad3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007094 mitotic spindle assembly checkpoint IEA
 biological_processGO:0051754 meiotic sister chromatid cohesion, centromeric IBA
 cellular_componentGO:0000778 condensed nuclear chromosome kinetochore IBA
 molecular_functionGO:0004672 protein kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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