ENSGALG00000008233


Gallus gallus

Features
Gene ID: ENSGALG00000008233
  
Biological name :BUB1
  
Synonyms : BUB1 / mitotic checkpoint serine/threonine-protein kinase BUB1
  
Possible biological names infered from orthology : BUB1 mitotic checkpoint serine/threonine kinase / mitotic checkpoint serine/threonine-protein kinase BUB1 isoform 2 / O43683
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 3107192
Gene end: 3126953
  
Corresponding Affymetrix probe sets: Gga.7180.1.S1_s_at (Chicken Array)   GgaAffx.5197.1.S1_at (Chicken Array)   GgaAffx.5197.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000013385
NCBI entrez gene - 421226     See in Manteia.
RefSeq - NM_001012870
RefSeq Peptide - NP_001012888
swissprot - F1NDM5
Ensembl - ENSGALG00000008233
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bub1ENSDARG00000077029Danio rerio
 BUB1ENSG00000169679Homo sapiens
 Bub1ENSMUSG00000027379Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BUB1B / BUB1 mitotic checkpoint serine/threonine kinase B / O60566* / Q9Z1S0* / Mitotic checkpoint serine/threonine-protein kinase BUB1 beta *ENSGALG0000003689218


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR013212  Mad3/Bub1 homology region 1
 IPR015661  Mitotic spindle checkpoint protein Bub1/Mad3
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007063 regulation of sister chromatid cohesion IEA
 biological_processGO:0007094 mitotic spindle assembly checkpoint IBA
 biological_processGO:0051754 meiotic sister chromatid cohesion, centromeric IBA
 biological_processGO:0051983 regulation of chromosome segregation IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0000778 condensed nuclear chromosome kinetochore IBA
 cellular_componentGO:0000942 condensed nuclear chromosome outer kinetochore IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0004672 protein kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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