Manteia

ENSDARG00000078187

Danio rerio

Features

Gene ID:	ENSDARG00000078187

Biological name :	slc12a5b

Synonyms :	slc12a5b / solute carrier family 12 (potassium/chloride transporter), member 5b

Possible biological names infered from orthology :	Q91V14 / Q9H2X9 / SLC12A5 / solute carrier family 12 member 5

Species:	Danio rerio

Chr. number:	8
Strand:	-1
Band:
Gene start:	37280532
Gene end:	37391372

Corresponding Affymetrix probe sets:

Cross references:	Ensembl peptide - ENSDARP00000018362 Ensembl peptide - ENSDARP00000119636 Ensembl peptide - ENSDARP00000155095 swissprot - E9QC71 swissprot - F1R5T1 ZFIN ID - ZDB-GENE-080707-1 Ensembl - ENSDARG00000078187

See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
SLC12A5	ENSGALG00000042199	Gallus gallus
Q9H2X9	ENSG00000124140	Homo sapiens
Q91V14	ENSMUSG00000017740	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
slc12a5a / solute carrier family 12 (potassium/chloride transporter), member 5a / Q91V14* / Q9H2X9* / SLC12A5* / solute carrier family 12 member 5*	ENSDARG00000075815	77
slc12a7b / solute carrier family 12 (potassium/chloride transporter), member 7b / Q9WVL3* / Q9Y666* / SLC12A7* / solute carrier family 12 member 7*	ENSDARG00000062058	65
slc12a4 / solute carrier family 12 (potassium/chloride transporter), member 4 / Q9JIS8* / Q9UP95* / solute carrier family 12 member 4*	ENSDARG00000014378	62
slc12a7a / solute carrier family 12 (potassium/chloride transporter), member 7a / Q9WVL3* / Q9Y666* / SLC12A7* / solute carrier family 12 member 7*	ENSDARG00000073756	61
slc12a2 / solute carrier family 12 (sodium/potassium/chloride transporter), member 2 / P55011* / solute carrier family 12 member 2*	ENSDARG00000104573	23
slc12a3 / solute carrier family 12 (sodium/chloride transporter), member 3 / P55017* / P59158* / solute carrier family 12 member 3*	ENSDARG00000013855	22
slc12a10.1 / solute carrier family 12 (sodium/potassium/chloride transporters), member 10, tandem duplicate 1	ENSDARG00000055313	22
slc12a10.2 / solute carrier family 12 (sodium/potassium/chloride transporters), member 10, tandem duplicate 2	ENSDARG00000071173	21
slc12a10.3 / slc12a10.3 solute carrier family 12 (sodium/potassium/chloride transporters), member 10, tandem duplicate 3	ENSDARG00000055253	21
zgc:153039	ENSDARG00000102724	18
A2BFP5 / slc12a9 / solute carrier family 12, member 9 / Q99MR3* / Q9BXP2*	ENSDARG00000060366	18
slc12a1 / solute carrier family 12 (sodium/potassium/chloride transporter), member 1 / Q13621* / solute carrier family 12 member 1*	ENSDARG00000098096	16
slc12a8 / solute carrier family 12, member 8 / A0AV02* / Q8VI23* / solute carrier family 12 (potassium/chloride transporters), member 8*	ENSDARG00000074384	14
si:cabz01090193.1 / Q9UHW9* / Q924N4* / Gm21985* / SLC12A6* / solute carrier family 12 member 6*	ENSDARG00000105485	12
CABZ01063543.1 / P55011* / SLC12A2* / solute carrier family 12 member 2*	ENSDARG00000113045	8

Protein motifs (from Interpro)

Interpro ID	Name
IPR000076	K/Cl co-transporter
IPR004841	Amino acid permease/ SLC12A domain
IPR004842	SLC12A transporter family
IPR018491	SLC12A transporter, C-terminal

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006811	ion transport	IEA
biological_process	GO:0007268	chemical synaptic transmission	IEA
biological_process	GO:0048919	posterior lateral line neuromast development	IMP
biological_process	GO:0055085	transmembrane transport	IEA
biological_process	GO:0060041	retina development in camera-type eye	IMP
biological_process	GO:0071805	potassium ion transmembrane transport	IEA
biological_process	GO:1902476	chloride transmembrane transport	IEA
cellular_component	GO:0005887	integral component of plasma membrane	IEA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
molecular_function	GO:0005215	transporter activity	IEA
molecular_function	GO:0015377	cation:chloride symporter activity	IEA
molecular_function	GO:0015379	potassium:chloride symporter activity	IEA

Pathways (from Reactome)

Pathway description

Cation-coupled Chloride cotransporters

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
ZFA:0000940	posterior lateral line neuromast	posterior lateral line neuromast decreased amount , abnormal posterior lateral line neuromast has fewer parts of type neuromast hair cell , abnormal	Show
ZFA:0001117	post-vent region	post-vent region decreased length , abnormal	Show
ZFA:0009310	retinal ganglion cell	retinal ganglion cell decreased functionality , abnormal	Show

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr