ENSDARG00000014378


Danio rerio

Features
Gene ID: ENSDARG00000014378
  
Biological name :slc12a4
  
Synonyms : slc12a4 / solute carrier family 12 (potassium/chloride transporter), member 4
  
Possible biological names infered from orthology : Q9JIS8 / Q9UP95 / solute carrier family 12 member 4
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 35282885
Gene end: 35314347
  
Corresponding Affymetrix probe sets: Dr.20057.1.S1_at (Zebrafish Array)   XM_686199_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000024612
NCBI entrez gene - 562826     See in Manteia.
RefSeq - XM_686199
swissprot - F1QBW2
ZFIN ID - ZDB-GENE-090218-27
Ensembl - ENSDARG00000014378
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SLC12A4ENSGALG00000034179Gallus gallus
 Q9UP95ENSG00000124067Homo sapiens
 Q9JIS8ENSMUSG00000017765Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
slc12a7b / solute carrier family 12 (potassium/chloride transporter), member 7b / Q9WVL3* / Q9Y666* / SLC12A7* / solute carrier family 12 member 7*ENSDARG0000006205868
slc12a5a / solute carrier family 12 (potassium/chloride transporter), member 5a / Q91V14* / Q9H2X9* / SLC12A5* / solute carrier family 12 member 5*ENSDARG0000007581565
slc12a5b / solute carrier family 12 (potassium/chloride transporter), member 5b / Q91V14* / Q9H2X9* / SLC12A5* / solute carrier family 12 member 5*ENSDARG0000007818765
slc12a7a / solute carrier family 12 (potassium/chloride transporter), member 7a / Q9WVL3* / Q9Y666* / SLC12A7* / solute carrier family 12 member 7*ENSDARG0000007375664
slc12a2 / solute carrier family 12 (sodium/potassium/chloride transporter), member 2 / P55011* / solute carrier family 12 member 2*ENSDARG0000010457326
slc12a3 / solute carrier family 12 (sodium/chloride transporter), member 3 / P55017* / P59158* / solute carrier family 12 member 3*ENSDARG0000001385525
slc12a10.1 / solute carrier family 12 (sodium/potassium/chloride transporters), member 10, tandem duplicate 1ENSDARG0000005531325
slc12a10.2 / solute carrier family 12 (sodium/potassium/chloride transporters), member 10, tandem duplicate 2ENSDARG0000007117323
slc12a10.3 / slc12a10.3 solute carrier family 12 (sodium/potassium/chloride transporters), member 10, tandem duplicate 3ENSDARG0000005525323
A2BFP5 / slc12a9 / solute carrier family 12, member 9 / Q99MR3* / Q9BXP2*ENSDARG0000006036620
zgc:153039ENSDARG0000010272420
slc12a1 / solute carrier family 12 (sodium/potassium/chloride transporter), member 1 / Q13621* / solute carrier family 12 member 1*ENSDARG0000009809618
slc12a8 / solute carrier family 12, member 8 / A0AV02* / Q8VI23* / solute carrier family 12 (potassium/chloride transporters), member 8*ENSDARG0000007438415
si:cabz01090193.1 / Q9UHW9* / Q924N4* / Gm21985* / SLC12A6* / solute carrier family 12 member 6*ENSDARG0000010548515
CABZ01063543.1 / P55011* / SLC12A2* / solute carrier family 12 member 2*ENSDARG0000011304510


Protein motifs (from Interpro)
Interpro ID Name
 IPR000076  K/Cl co-transporter
 IPR000622  K/Cl co-transporter 1
 IPR004841  Amino acid permease/ SLC12A domain
 IPR004842  SLC12A transporter family
 IPR018491  SLC12A transporter, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0007268 chemical synaptic transmission IBA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071477 cellular hypotonic salinity response IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 biological_processGO:1902476 chloride transmembrane transport IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005215 transporter activity IEA
 molecular_functionGO:0015377 cation:chloride symporter activity IEA
 molecular_functionGO:0015379 potassium:chloride symporter activity IBA


Pathways (from Reactome)
Pathway description
Cation-coupled Chloride cotransporters


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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