ENSDARG00000013855


Danio rerio

Features
Gene ID: ENSDARG00000013855
  
Biological name :slc12a3
  
Synonyms : slc12a3 / solute carrier family 12 (sodium/chloride transporter), member 3
  
Possible biological names infered from orthology : P55017 / P59158 / solute carrier family 12 member 3
  
Species: Danio rerio
  
Chr. number: 18
Strand: 1
Band:
Gene start: 17583479
Gene end: 17598755
  
Corresponding Affymetrix probe sets: Dr.12000.1.S1_at (Zebrafish Array)   Dr.12000.2.S1_at (Zebrafish Array)   NM_001045080_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000155152
Ensembl peptide - ENSDARP00000025500
NCBI entrez gene - 565439     See in Manteia.
RefSeq - NM_001045080
RefSeq Peptide - NP_001038545
swissprot - A9JRV0
swissprot - Q1LX46
ZFIN ID - ZDB-GENE-030131-9505
Ensembl - ENSDARG00000013855
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SLC12A3ENSGALG00000002957Gallus gallus
 P55017ENSG00000070915Homo sapiens
 P59158ENSMUSG00000031766Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
slc12a10.1 / solute carrier family 12 (sodium/potassium/chloride transporters), member 10, tandem duplicate 1ENSDARG0000005531356
slc12a10.3 / slc12a10.3 solute carrier family 12 (sodium/potassium/chloride transporters), member 10, tandem duplicate 3ENSDARG0000005525352
slc12a10.2 / solute carrier family 12 (sodium/potassium/chloride transporters), member 10, tandem duplicate 2ENSDARG0000007117350
slc12a2 / solute carrier family 12 (sodium/potassium/chloride transporter), member 2 / P55011* / solute carrier family 12 member 2*ENSDARG0000010457349
slc12a1 / solute carrier family 12 (sodium/potassium/chloride transporter), member 1 / Q13621* / solute carrier family 12 member 1*ENSDARG0000009809634
slc12a4 / solute carrier family 12 (potassium/chloride transporter), member 4 / Q9JIS8* / Q9UP95* / solute carrier family 12 member 4*ENSDARG0000001437827
slc12a7a / solute carrier family 12 (potassium/chloride transporter), member 7a / Q9WVL3* / Q9Y666* / SLC12A7* / solute carrier family 12 member 7*ENSDARG0000007375626
slc12a7b / solute carrier family 12 (potassium/chloride transporter), member 7b / Q9WVL3* / Q9Y666* / SLC12A7* / solute carrier family 12 member 7*ENSDARG0000006205826
slc12a5b / solute carrier family 12 (potassium/chloride transporter), member 5b / Q91V14* / Q9H2X9* / SLC12A5* / solute carrier family 12 member 5*ENSDARG0000007818725
slc12a5a / solute carrier family 12 (potassium/chloride transporter), member 5a / Q91V14* / Q9H2X9* / SLC12A5* / solute carrier family 12 member 5*ENSDARG0000007581524
zgc:153039ENSDARG0000010272423
A2BFP5 / slc12a9 / solute carrier family 12, member 9 / Q99MR3* / Q9BXP2*ENSDARG0000006036621
CABZ01063543.1 / P55011* / SLC12A2* / solute carrier family 12 member 2*ENSDARG0000011304517
slc12a8 / solute carrier family 12, member 8 / A0AV02* / Q8VI23* / solute carrier family 12 (potassium/chloride transporters), member 8*ENSDARG0000007438416
si:cabz01090193.1 / Q9UHW9* / Q924N4* / Gm21985* / SLC12A6* / solute carrier family 12 member 6*ENSDARG000001054855


Protein motifs (from Interpro)
Interpro ID Name
 IPR002948  Thiazide-sensitive Na-K-Cl co-transporter
 IPR004841  Amino acid permease/ SLC12A domain
 IPR004842  SLC12A transporter family
 IPR013612  Amino acid permease, N-terminal
 IPR018491  SLC12A transporter, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0035844 cloaca development IMP
 biological_processGO:0039023 pronephric duct morphogenesis IMP
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:1902476 chloride transmembrane transport IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005215 transporter activity IEA
 molecular_functionGO:0015377 cation:chloride symporter activity IEA


Pathways (from Reactome)
Pathway description
Cation-coupled Chloride cotransporters


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000150 pronephric duct pronephric duct epithelium morphology , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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