ENSDARG00000078694


Danio rerio

Features
Gene ID: ENSDARG00000078694
  
Biological name :phlpp1
  
Synonyms : PH domain and leucine rich repeat protein phosphatase 1 / phlpp1
  
Possible biological names infered from orthology : O60346 / PH domain leucine-rich repeat-containing protein phosphatase 1 / Q8CHE4
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 258698
Gene end: 283376
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000129301
Ensembl peptide - ENSDARP00000153247
Ensembl peptide - ENSDARP00000153597
swissprot - X1WGE6
ZFIN ID - ZDB-GENE-131127-271
Ensembl - ENSDARG00000078694
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PHLPP1ENSGALG00000012888Gallus gallus
 O60346ENSG00000081913Homo sapiens
 Phlpp1ENSMUSG00000044340Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
phlpp2 / PH domain and leucine rich repeat protein phosphatase 2 / Q6ZVD8*ENSDARG0000009025510


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR001932  PPM-type phosphatase domain
 IPR003591  Leucine-rich repeat, typical subtype
 IPR011993  PH-like domain superfamily
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0046328 regulation of JNK cascade IBA
 biological_processGO:0051896 regulation of protein kinase B signaling IBA
 biological_processGO:0090036 regulation of protein kinase C signaling IBA
 biological_processGO:1900744 regulation of p38MAPK cascade IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0031965 nuclear membrane IBA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity IBA


Pathways (from Reactome)
Pathway description
Negative regulation of the PI3K/AKT network


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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