ENSGALG00000012888


Gallus gallus

Features
Gene ID: ENSGALG00000012888
  
Biological name :PHLPP1
  
Synonyms : PH domain and leucine rich repeat protein phosphatase 1 / PHLPP1
  
Possible biological names infered from orthology : O60346 / PH domain leucine-rich repeat-containing protein phosphatase 1 / Q8CHE4
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 68241488
Gene end: 68371532
  
Corresponding Affymetrix probe sets: Gga.19253.1.S1_at (Chicken Array)   GgaAffx.21243.1.S1_s_at (Chicken Array)   GgaAffx.24030.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000036383
NCBI entrez gene - 420904     See in Manteia.
RefSeq - XM_015282197
swissprot - F1NJB8
Ensembl - ENSGALG00000012888
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 phlpp1ENSDARG00000078694Danio rerio
 O60346ENSG00000081913Homo sapiens
 Phlpp1ENSMUSG00000044340Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PHLPP2 / PH domain and leucine rich repeat protein phosphatase 2 / Q6ZVD8* / Q8BXA7* / PH domain leucine-rich repeat-containing protein phosphatase 2 *ENSGALG0000000087545


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR001849  Pleckstrin homology domain
 IPR001932  PPM-type phosphatase domain
 IPR003591  Leucine-rich repeat, typical subtype
 IPR011993  PH-like domain superfamily
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002667 regulation of T cell anergy IEA
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0009649 entrainment of circadian clock IEA
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0043408 regulation of MAPK cascade IEA
 biological_processGO:0046328 regulation of JNK cascade IEA
 biological_processGO:0051896 regulation of protein kinase B signaling IBA
 biological_processGO:0051898 negative regulation of protein kinase B signaling IEA
 biological_processGO:0090036 regulation of protein kinase C signaling IBA
 biological_processGO:1900744 regulation of p38MAPK cascade IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0031965 nuclear membrane IBA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity IBA


Pathways (from Reactome)
Pathway description
Negative regulation of the PI3K/AKT network


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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