ENSDARG00000088439


Danio rerio

Features
Gene ID: ENSDARG00000088439
  
Biological name :gm2a
  
Synonyms : gm2a / GM2 ganglioside activator
  
Possible biological names infered from orthology : Ganglioside GM2 activator / P17900 / Q60648
  
Species: Danio rerio
  
Chr. number: 14
Strand: 1
Band:
Gene start: 26224541
Gene end: 26227970
  
Corresponding Affymetrix probe sets: Dr.2113.1.S1_at (Zebrafish Array)   Dr.2113.2.S1_a_at (Zebrafish Array)   NM_001017831_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000133664
Ensembl peptide - ENSDARP00000106218
NCBI entrez gene - 550529     See in Manteia.
RefSeq - NM_001017831
RefSeq - XM_005173119
RefSeq Peptide - NP_001017831
swissprot - Q568N7
swissprot - A0A0R4IJ69
ZFIN ID - ZDB-GENE-050417-373
Ensembl - ENSDARG00000088439
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GM2AENSGALG00000027534Gallus gallus
 GM2AENSG00000196743Homo sapiens
 Gm2aENSMUSG00000000594Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LO018208.1 / GM2A* / P17900* / GM2 ganglioside activator*ENSDARG0000010743143


Protein motifs (from Interpro)
Interpro ID Name
 IPR003172  MD-2-related lipid-recognition domain
 IPR028996  Ganglioside GM2 activator


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006689 ganglioside catabolic process IEA
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0008047 enzyme activator activity IEA


Pathways (from Reactome)
Pathway description
Glycosphingolipid metabolism
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000052113 hexa / hexosaminidase A (alpha polypeptide) / P29416* / P06865* / AC009690.1* / hexosaminidase subunit alpha* / Beta-hexosaminidase subunit alpha *  / reaction
 ENSDARG00000034368 hexb / hexosaminidase B (beta polypeptide) / P07686* / P20060* / hexosaminidase subunit beta* / Beta-hexosaminidase subunit beta *  / reaction






 

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