ENSDARG00000091298


Danio rerio

Features
Gene ID: ENSDARG00000091298
  
Biological name :pmela
  
Synonyms : pmela / premelanosome protein a
  
Possible biological names infered from orthology : P40967 / PMEL / premelanosome protein
  
Species: Danio rerio
  
Chr. number: 11
Strand: 1
Band:
Gene start: 3254252
Gene end: 3272020
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000107876
Ensembl peptide - ENSDARP00000134932
swissprot - A0A0R4IIU6
swissprot - F1R9D2
ZFIN ID - ZDB-GENE-030131-9818
Ensembl - ENSDARG00000091298
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PMELENSGALG00000035350Gallus gallus
 PMELENSG00000185664Homo sapiens
 PmelENSMUSG00000025359Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pmelb / premelanosome protein b / PMEL* / P40967* / premelanosome protein*ENSDARG0000003376035
gpnmb / glycoprotein (transmembrane) nmb / Q14956* / Q99P91* / glycoprotein nmb* / Transmembrane glycoprotein NMB *ENSDARG0000006268817


Protein motifs (from Interpro)
Interpro ID Name
 IPR000601  PKD domain
 IPR013783  Immunoglobulin-like fold
 IPR022409  PKD/Chitinase domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0032438 melanosome organization IMP
 biological_processGO:0048066 developmental pigmentation IMP
 biological_processGO:0048069 eye pigmentation IMP
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0042470 melanosome IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye decreased size , abnormal
eye neoplastic , abnormal
eye aplastic , abnormal
eye quality , abnormal
Show

 ZFA:0000144 retinal pigmented epithelium retinal pigmented epithelium unpigmented , abnormal
retinal pigmented epithelium melanosome morphology , abnormal
retinal pigmented epithelium melanosome decreased amount , abnormal
Show

 ZFA:0000152 retina retina degenerate , abnormal
Show

 ZFA:0000282 sensory system sensory system quality , abnormal
Show

 ZFA:0000396 nervous system nervous system quality , abnormal
Show

 ZFA:0001094 whole organism whole organism has fewer parts of type melanocyte , abnormal
Show

 ZFA:0005220 larval melanophore stripe larval melanophore stripe low saturation , abnormal
Show

 ZFA:0005558 orbit orbit neoplasm protruding , abnormal
Show

 ZFA:0009090 pigment cell pigment cell quality , abnormal
Show

 ZFA:0009091 melanocyte melanocyte spatial pattern , abnormal
melanocyte low saturation , abnormal
melanocyte decreased size , abnormal
melanocyte broken , abnormal
melanocyte aggregated , abnormal
melanocyte decreased pigmentation , abnormal
melanocyte melanosome degenerate , abnormal
melanocyte intensity , abnormal
melanocyte morphology , abnormal
melanocyte irregular spatial pattern , abnormal
Show

 ZFA:0009127 photoreceptor cell photoreceptor cell photoreceptor outer segment morphology , abnormal
photoreceptor cell photoreceptor outer segment structure , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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