Manteia

ENSDARG00000094526

Danio rerio

Features

Gene ID:	ENSDARG00000094526

Biological name :	ksr2

Synonyms :	kinase suppressor of ras 2 / ksr2

Possible biological names infered from orthology :	Q6VAB6

Species:	Danio rerio

Chr. number:	5
Strand:	-1
Band:
Gene start:	12272632
Gene end:	12525441

Corresponding Affymetrix probe sets:	Dr.22750.1.A1_at (Zebrafish Array)

Cross references:	Ensembl peptide - ENSDARP00000105920 Ensembl peptide - ENSDARP00000144265 Ensembl peptide - ENSDARP00000133115 NCBI entrez gene - 569127 See in Manteia. swissprot - A0A286YAS8 swissprot - A0A0R4IHD1 swissprot - F5H8P1 ZFIN ID - ZDB-GENE-030131-8047 Ensembl - ENSDARG00000094526

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
ksr1a / kinase suppressor of ras 1a / KSR1* / Q61097* / Q8IVT5* / kinase suppressor of ras 1* / Mus musculus kinase suppressor of ras 1 (Ksr1), transcript variant 2, mRNA.*	ENSDARG00000068714	48
ksr1b / kinase suppressor of ras 1b / KSR1* / Q61097* / Q8IVT5* / kinase suppressor of ras 1* / Mus musculus kinase suppressor of ras 1 (Ksr1), transcript variant 2, mRNA.*	ENSDARG00000030933	46
braf / B-Raf proto-oncogene, serine/threonine kinase / P15056* / P28028* / Serine/threonine-protein kinase B-raf *	ENSDARG00000017661	18
raf1b / Raf-1 proto-oncogene, serine/threonine kinase b / RAF1* / Q99N57* / P04049* / Raf-1 proto-oncogene, serine/threonine kinase* / Mus musculus v-raf-leukemia viral onco 1 (Raf1), trans...	ENSDARG00000059406	17
raf1a / Raf-1 proto-oncogene, serine/threonine kinase a / RAF1* / Q99N57* / P04049* / Raf-1 proto-oncogene, serine/threonine kinase* / Mus musculus v-raf-leukemia viral onco 1 (Raf1), trans...	ENSDARG00000096415	16
araf / A-Raf proto-oncogene, serine/threonine kinase / P04627* / P10398* / Serine/threonine-protein kinase A-Raf *	ENSDARG00000054533	16
si:ch73-263f13.1 / KSR2* / Q6VAB6* / kinase suppressor of ras 2*	ENSDARG00000094172	11
raf1a / Raf-1 proto-oncogene, serine/threonine kinase a / RAF1* / Q99N57* / P04049* / Raf-1 proto-oncogene, serine/threonine kinase* / Mus musculus v-raf-leukemia viral onco 1 (Raf1), trans...	ENSDARG00000102328	4

Protein motifs (from Interpro)

Interpro ID	Name
IPR000719	Protein kinase domain
IPR001245	Serine-threonine/tyrosine-protein kinase, catalytic domain
IPR002219	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
IPR008271	Serine/threonine-protein kinase, active site
IPR011009	Protein kinase-like domain superfamily
IPR025561	Kinase suppressor of RAS, SAM-like domain

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006468	protein phosphorylation	IEA
biological_process	GO:0019722	calcium-mediated signaling	IBA
biological_process	GO:0035556	intracellular signal transduction	IEA
biological_process	GO:0043410	positive regulation of MAPK cascade	IBA
cellular_component	GO:0005622	intracellular	IEA
cellular_component	GO:0005829	cytosol	IBA
cellular_component	GO:0005886	plasma membrane	IBA
molecular_function	GO:0004672	protein kinase activity	IEA
molecular_function	GO:0004871	obsolete signal transducer activity	IBA
molecular_function	GO:0005524	ATP binding	IEA
molecular_function	GO:0046872	metal ion binding	IEA

Pathways (from Reactome)

Pathway description

MAP2K and MAPK activation

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr