ENSDARG00000068714


Danio rerio

Features
Gene ID: ENSDARG00000068714
  
Biological name :ksr1a
  
Synonyms : kinase suppressor of ras 1a / ksr1a
  
Possible biological names infered from orthology : kinase suppressor of ras 1 / KSR1 / Mus musculus kinase suppressor of ras 1 (Ksr1), transcript variant 2, mRNA. / Q61097 / Q8IVT5
  
Species: Danio rerio
  
Chr. number: 10
Strand: 1
Band:
Gene start: 37173029
Gene end: 37256989
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000112861
Ensembl peptide - ENSDARP00000117861
Ensembl peptide - ENSDARP00000155605
swissprot - E9QDU0
swissprot - F1QN59
ZFIN ID - ZDB-GENE-091113-34
Ensembl - ENSDARG00000068714
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KSR1ENSGALG00000005685Gallus gallus
 KSR1ENSG00000141068Homo sapiens
 Ksr1ENSMUSG00000018334Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ksr1b / kinase suppressor of ras 1b / KSR1* / Q61097* / Q8IVT5* / kinase suppressor of ras 1* / Mus musculus kinase suppressor of ras 1 (Ksr1), transcript variant 2, mRNA.*ENSDARG0000003093360
ksr2 / kinase suppressor of ras 2 / Q6VAB6*ENSDARG0000009452645
braf / B-Raf proto-oncogene, serine/threonine kinase / P15056* / P28028* / Serine/threonine-protein kinase B-raf *ENSDARG0000001766116
raf1a / Raf-1 proto-oncogene, serine/threonine kinase a / RAF1* / Q99N57* / P04049* / Raf-1 proto-oncogene, serine/threonine kinase* / Mus musculus v-raf-leukemia viral onco 1 (Raf1), trans...ENSDARG0000009641515
raf1b / Raf-1 proto-oncogene, serine/threonine kinase b / RAF1* / Q99N57* / P04049* / Raf-1 proto-oncogene, serine/threonine kinase* / Mus musculus v-raf-leukemia viral onco 1 (Raf1), trans...ENSDARG0000005940614
araf / A-Raf proto-oncogene, serine/threonine kinase / P04627* / P10398* / Serine/threonine-protein kinase A-Raf *ENSDARG0000005453313
si:ch73-263f13.1 / KSR2* / Q6VAB6* / kinase suppressor of ras 2*ENSDARG000000941726
raf1a / Raf-1 proto-oncogene, serine/threonine kinase a / RAF1* / Q99N57* / P04049* / Raf-1 proto-oncogene, serine/threonine kinase* / Mus musculus v-raf-leukemia viral onco 1 (Raf1), trans...ENSDARG000001023284


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR011009  Protein kinase-like domain superfamily
 IPR025561  Kinase suppressor of RAS, SAM-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IBA
 biological_processGO:0007265 Ras protein signal transduction IBA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043410 positive regulation of MAPK cascade IBA
 cellular_componentGO:0005783 endoplasmic reticulum IBA
 cellular_componentGO:0016020 membrane IBA
 molecular_functionGO:0004672 protein kinase activity IBA
 molecular_functionGO:0004871 obsolete signal transducer activity IBA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
RAF activation
MAP2K and MAPK activation
Negative regulation of MAPK pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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