ENSDARG00000094704


Danio rerio

Features
Gene ID: ENSDARG00000094704
  
Biological name :bcl2a
  
Synonyms : bcl2a / BCL2, apoptosis regulator a
  
Possible biological names infered from orthology : Apoptosis regulator Bcl-2 / BCL2 / BCL2, apoptosis regulator / P10415 / P10417
  
Species: Danio rerio
  
Chr. number: 24
Strand: -1
Band:
Gene start: 28137210
Gene end: 28229618
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000120749
NCBI entrez gene - 570772     See in Manteia.
swissprot - Q564A4
ZFIN ID - ZDB-GENE-051012-1
Ensembl - ENSDARG00000094704
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BCL2ENSGALG00000012885Gallus gallus
 BCL2ENSG00000171791Homo sapiens
 Bcl2ENSMUSG00000057329Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
bcl2b / BCL2, apoptosis regulator b / BCL2* / P10417* / P10415* / BCL2, apoptosis regulator* / Apoptosis regulator Bcl-2 *ENSDARG0000008910946
bcl2l1 / bcl2-like 1 / Q07817* / Q64373* / Mus musculus BCL2-like 1 (Bcl2l1), transcript variant 5, mRNA.*ENSDARG0000000843432


Protein motifs (from Interpro)
Interpro ID Name
 IPR002475  Bcl2-like
 IPR003093  Apoptosis regulator, Bcl-2 protein, BH4
 IPR013278  Apoptosis regulator, Bcl-2
 IPR013279  Apoptosis regulator, Bcl-X
 IPR020717  Apoptosis regulator, Bcl-2, BH1 motif, conserved site
 IPR020726  Apoptosis regulator, Bcl-2, BH2 motif, conserved site
 IPR026298  Blc2 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage IBA
 biological_processGO:0042981 regulation of apoptotic process IGI
 biological_processGO:0043066 negative regulation of apoptotic process IGI
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IDA
 biological_processGO:0097192 extrinsic apoptotic signaling pathway in absence of ligand IBA
 cellular_componentGO:0005741 mitochondrial outer membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0042803 protein homodimerization activity IBA
 molecular_functionGO:0046982 protein heterodimerization activity IPI


Pathways (from Reactome)
Pathway description
The NLRP1 inflammasome


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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