ENSDARG00000098367


Danio rerio

Features
Gene ID: ENSDARG00000098367
  
Biological name :srp54
  
Synonyms : signal recognition particle 54 / srp54
  
Possible biological names infered from orthology : P14576 / P61011 / signal recognition particle 54B / Signal recognition particle 54 kDa protein / Srp54b
  
Species: Danio rerio
  
Chr. number: 17
Strand: 1
Band:
Gene start: 10074360
Gene end: 10090026
  
Corresponding Affymetrix probe sets: Dr.7990.1.S1_at (Zebrafish Array)   NM_200988_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000131757
Ensembl peptide - ENSDARP00000139136
NCBI entrez gene - 393963     See in Manteia.
RefSeq - NM_200988
RefSeq Peptide - NP_957282
swissprot - Q7ZVN5
ZFIN ID - ZDB-GENE-040426-818
Ensembl - ENSDARG00000098367
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SRP54ENSGALG00000023135Gallus gallus
 SRP54ENSG00000100883Homo sapiens
 Srp54ENSMUSG00000112449Mus musculus
 Srp54ENSMUSG00000073079Mus musculus
 Srp54bENSMUSG00000079108Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000897  Signal recognition particle, SRP54 subunit, GTPase domain
 IPR003593  AAA+ ATPase domain
 IPR004125  Signal recognition particle, SRP54 subunit, M-domain
 IPR006325  Signal recognition particle, SRP54 subunit, eukaryotic
 IPR013822  Signal recognition particle, SRP54 subunit, helical bundle
 IPR022941  Signal recognition particle, SRP54 subunit
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006614 SRP-dependent cotranslational protein targeting to membrane IEA
 biological_processGO:0045047 protein targeting to ER IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005786 signal recognition particle, endoplasmic reticulum targeting IEA
 cellular_componentGO:0048500 signal recognition particle IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0008312 7S RNA binding IEA


Pathways (from Reactome)
Pathway description
SRP-dependent cotranslational protein targeting to membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001117 post-vent region post-vent region neutrophil chemotaxis disrupted , abnormal
post-vent region neutrophil decreased amount , abnormal
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 ZFA:0001249 exocrine pancreas exocrine pancreas morphology , abnormal
Show

 ZFA:0009327 neutrophil neutrophil decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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