ENSMUSG00000073079


Mus musculus

Features
Gene ID: ENSMUSG00000073079
  
Biological name :Srp54
  
Synonyms : P14576 / Signal recognition particle 54 kDa protein / Srp54
  
Possible biological names infered from orthology : P61011 / signal recognition particle 54
  
Species: Mus musculus
  
Chr. number: 12
Strand: 1
Band: C1
Gene start: 55080262
Gene end: 55115367
  
Corresponding Affymetrix probe sets: 10395739 (MoGene1.0st)   10395788 (MoGene1.0st)   1416153_at (Mouse Genome 430 2.0 Array)   1416154_at (Mouse Genome 430 2.0 Array)   1425665_a_at (Mouse Genome 430 2.0 Array)   1430476_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000152448
Ensembl peptide - ENSMUSP00000152764
Ensembl peptide - ENSMUSP00000152541
Ensembl peptide - ENSMUSP00000021407
NCBI entrez gene - 24067     See in Manteia.
MGI - MGI:1346087
RefSeq - NM_011899
RefSeq - XM_006515868
RefSeq Peptide - NP_036029
swissprot - A0A1Y7VJJ0
swissprot - P14576
swissprot - A0A1W2P809
Ensembl - ENSMUSG00000073079
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 srp54ENSDARG00000098367Danio rerio
 SRP54ENSGALG00000023135Gallus gallus
 SRP54ENSG00000100883Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Srp54 / P14576 / Signal recognition particle 54 kDa protein / P61011* / signal recognition particle 54*ENSMUSG00000112449100
Srp54b / signal recognition particle 54B / SRP54* / P61011* / signal recognition particle 54*ENSMUSG0000007910899


Protein motifs (from Interpro)
Interpro ID Name
 IPR000897  Signal recognition particle, SRP54 subunit, GTPase domain
 IPR003593  AAA+ ATPase domain
 IPR004125  Signal recognition particle, SRP54 subunit, M-domain
 IPR006325  Signal recognition particle, SRP54 subunit, eukaryotic
 IPR013822  Signal recognition particle, SRP54 subunit, helical bundle
 IPR022941  Signal recognition particle, SRP54 subunit
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR036225  SRP/SRP receptor, N-terminal
 IPR036891  Signal recognition particle, SRP54 subunit, M-domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006614 SRP-dependent cotranslational protein targeting to membrane ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005786 signal recognition particle, endoplasmic reticulum targeting ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0048500 signal recognition particle IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003924 GTPase activity ISO
 molecular_functionGO:0005525 GTP binding ISO
 molecular_functionGO:0008144 drug binding ISO
 molecular_functionGO:0008312 7S RNA binding ISO
 molecular_functionGO:0019003 GDP binding ISO
 molecular_functionGO:0030942 endoplasmic reticulum signal peptide binding ISO
 molecular_functionGO:0043021 ribonucleoprotein complex binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr