ENSMUSG00000112449


Mus musculus

Features
Gene ID: ENSMUSG00000112449
  
Biological name :Srp54
  
Synonyms : P14576 / Signal recognition particle 54 kDa protein / Srp54
  
Possible biological names infered from orthology : P61011 / signal recognition particle 54
  
Species: Mus musculus
  
Chr. number: 12
Strand: 1
Band: C1
Gene start: 55155104
Gene end: 55189573
  
Corresponding Affymetrix probe sets: 10395739 (MoGene1.0st)   10395788 (MoGene1.0st)   1416153_at (Mouse Genome 430 2.0 Array)   1416154_at (Mouse Genome 430 2.0 Array)   1425665_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000151868
Ensembl peptide - ENSMUSP00000106336
NCBI entrez gene - 665155     See in Manteia.
MGI - MGI:3714357
MGI - MGI:1346087
RefSeq - NM_001100109
RefSeq - XM_006516155
RefSeq Peptide - NP_001093579
swissprot - A0A1W2P809
swissprot - P14576
Ensembl - ENSMUSG00000112449
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 srp54ENSDARG00000098367Danio rerio
 SRP54ENSGALG00000023135Gallus gallus
 SRP54ENSG00000100883Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Srp54 / P14576 / Signal recognition particle 54 kDa protein / P61011* / signal recognition particle 54*ENSMUSG00000073079100
Srp54b / signal recognition particle 54B / SRP54* / P61011* / signal recognition particle 54*ENSMUSG0000007910899


Protein motifs (from Interpro)
Interpro ID Name
 IPR000897  Signal recognition particle, SRP54 subunit, GTPase domain
 IPR003593  AAA+ ATPase domain
 IPR004125  Signal recognition particle, SRP54 subunit, M-domain
 IPR006325  Signal recognition particle, SRP54 subunit, eukaryotic
 IPR013822  Signal recognition particle, SRP54 subunit, helical bundle
 IPR022941  Signal recognition particle, SRP54 subunit
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR036225  SRP/SRP receptor, N-terminal
 IPR036891  Signal recognition particle, SRP54 subunit, M-domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006614 SRP-dependent cotranslational protein targeting to membrane IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005786 signal recognition particle, endoplasmic reticulum targeting ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0048500 signal recognition particle IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0008144 drug binding ISO
 molecular_functionGO:0008312 7S RNA binding ISO
 molecular_functionGO:0019003 GDP binding ISO
 molecular_functionGO:0030942 endoplasmic reticulum signal peptide binding ISO
 molecular_functionGO:0043021 ribonucleoprotein complex binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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