ENSDARG00000098578


Danio rerio

Features
Gene ID: ENSDARG00000098578
  
Biological name :pdgfab
  
Synonyms : pdgfab / platelet-derived growth factor alpha polypeptide b
  
Possible biological names infered from orthology : P04085 / PDGFA / platelet derived growth factor subunit A
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 12924930
Gene end: 12970428
  
Corresponding Affymetrix probe sets: Dr.21618.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000134014
Ensembl peptide - ENSDARP00000135004
Ensembl peptide - ENSDARP00000140240
swissprot - A0A0R4IF94
swissprot - A0A0R4IHM5
swissprot - A0A0R4IXE1
ZFIN ID - ZDB-GENE-060929-124
Ensembl - ENSDARG00000098578
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PDGFAENSGALG00000003642Gallus gallus
 PDGFAENSG00000197461Homo sapiens
 PdgfaENSMUSG00000025856Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pdgfaa / platelet-derived growth factor alpha polypeptide a / PDGFA* / P04085* / platelet derived growth factor subunit A*ENSDARG0000011006951
pdgfaa / platelet-derived growth factor alpha polypeptide a / PDGFA* / P04085* / platelet derived growth factor subunit A*ENSDARG0000010937151
pdgfba / platelet-derived growth factor beta polypeptide a / PDGFB* / P01127* / platelet derived growth factor subunit B* / platelet derived growth factor, B polypeptide*ENSDARG000000867783
pdgfbb / platelet-derived growth factor beta polypeptide b / PDGFB* / P01127* / platelet derived growth factor subunit B* / platelet derived growth factor, B polypeptide*ENSDARG000000381392


Protein motifs (from Interpro)
Interpro ID Name
 IPR000072  PDGF/VEGF domain
 IPR006782  Platelet-derived growth factor, N-terminal
 IPR023581  Platelet-derived growth factor, conserved site
 IPR029034  Cystine-knot cytokine


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0008083 growth factor activity IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation
PIP3 activates AKT signaling
Downstream signal transduction
Signaling by PDGF
Non-integrin membrane-ECM interactions
RAF/MAP kinase cascade
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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