ENSDARG00000098650


Danio rerio

Features
Gene ID: ENSDARG00000098650
  
Biological name :iqgap3
  
Synonyms : iqgap3 / IQ motif containing GTPase activating protein 3
  
Possible biological names infered from orthology : Q86VI3
  
Species: Danio rerio
  
Chr. number: 16
Strand: -1
Band:
Gene start: 55208398
Gene end: 55259199
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000131130
NCBI entrez gene - 100537977     See in Manteia.
RefSeq - NM_001308967
RefSeq Peptide - NP_001295896
swissprot - A0A0G2KFQ1
ZFIN ID - ZDB-GENE-160226-1
Ensembl - ENSDARG00000098650
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IQGAP3ENSG00000183856Homo sapiens
 Iqgap3ENSMUSG00000028068Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
iqgap1 / IQ motif containing GTPase activating protein 1 / P46940*ENSDARG0000007888855
iqgap2 / IQ motif containing GTPase activating protein 2 / Q13576* / Q3UQ44* / Ras GTPase-activating-like protein IQGAP2 *ENSDARG0000006001052


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR000593  RasGAP protein, C-terminal
 IPR001202  WW domain
 IPR001715  Calponin homology domain
 IPR001936  Ras GTPase-activating domain
 IPR008936  Rho GTPase activation protein
 IPR023152  Ras GTPase-activating protein, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0043087 regulation of GTPase activity IEA
 biological_processGO:0048870 cell motility IMP
 biological_processGO:0060027 convergent extension involved in gastrulation IMP


Pathways (from Reactome)
Pathway description
RHO GTPases activate IQGAPs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000132 neural plate neural plate increased width , abnormal
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 ZFA:0000135 notochord notochord increased width , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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