ENSDARG00000078888


Danio rerio

Features
Gene ID: ENSDARG00000078888
  
Biological name :iqgap1
  
Synonyms : iqgap1 / IQ motif containing GTPase activating protein 1
  
Possible biological names infered from orthology : P46940 / Q9JKF1 / Ras GTPase-activating-like protein IQGAP1
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 50641919
Gene end: 50764714
  
Corresponding Affymetrix probe sets: Dr.17687.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000098704
swissprot - E7FBD5
ZFIN ID - ZDB-GENE-050809-24
Ensembl - ENSDARG00000078888
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IQGAP1ENSGALG00000030162Gallus gallus
 IQGAP1ENSG00000140575Homo sapiens
 Iqgap1ENSMUSG00000030536Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
iqgap2 / IQ motif containing GTPase activating protein 2 / Q13576* / Q3UQ44* / Ras GTPase-activating-like protein IQGAP2 *ENSDARG0000006001060
iqgap3 / IQ motif containing GTPase activating protein 3 / Q86VI3*ENSDARG0000009865055


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR000593  RasGAP protein, C-terminal
 IPR001202  WW domain
 IPR001715  Calponin homology domain
 IPR001936  Ras GTPase-activating domain
 IPR008936  Rho GTPase activation protein
 IPR023152  Ras GTPase-activating protein, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0043087 regulation of GTPase activity IEA
 biological_processGO:0060070 canonical Wnt signaling pathway IEA


Pathways (from Reactome)
Pathway description
Nephrin family interactions
RHO GTPases activate IQGAPs
MAP2K and MAPK activation
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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